Regulatory switch at the cytoplasmic interface controls TRPV channel gating
Temperature-sensitive transient receptor potential vanilloid (thermoTRPV) channels are activated by ligands and heat, and are involved in various physiological processes.
Lejla Zubcevic+4 more
doaj +1 more source
Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake [PDF]
Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects.
Le Merrer, Julie, Stephens, David N
core +1 more source
Adolescent methylphenidate treatment differentially alters adult impulsivity and hyperactivity in the Spontaneously Hypertensive Rat model of ADHD [PDF]
Impulsivity and hyperactivity are two facets of attention deficit/hyperactivity disorder (ADHD). Impulsivity is expressed as reduced response inhibition capacity, an executive control mechanism that prevents premature execution of an intermittently ...
Bardo, M. T.+3 more
core +1 more source
Current Desensitization Strategies in Heart Transplantation
Heart transplant candidates sensitized to HLA antigens wait longer for transplant, are at increased risk of dying while waiting, and may not be listed at all.
Marlena V. Habal
doaj +1 more source
The psychology and neurobiology of addiction: an incentive-sensitization view.
The question of addiction specifically concerns (1), the process by which drug-taking behavior, in certain individuals, evolves into compulsive patterns of drug-seeking and drug-taking behavior that take place at the expense of most other activities and (
T. Robinson, K. Berridge
semanticscholar +1 more source
Hidden Patterns of Anti-HLA Class I Alloreactivity Revealed Through Machine Learning
Detection of alloreactive anti-HLA antibodies is a frequent and mandatory test before and after organ transplantation to determine the antigenic targets of the antibodies.
Angeliki G. Vittoraki+12 more
doaj +1 more source
SENSITIZATION OF PARENTS OF CHILDREN OF PEERS INVOLVED IN THE INCLUSIVE PROCESS IN MACEDONIA AND BOSNIA AND HERZEGOVINA [PDF]
The global trend of incorporating students with disabilities into mainstream education is on the rise, a phenomenon observed in countries like Macedonia and Bosnia and Herzegovina. However, the attitudes of parents with typically developing children play
Aleksandra Jakovchevska+2 more
doaj +1 more source
Organizational leadership perspectives in implementation of the One Health approach: A case of the Zoonotic Disease Unit and core One Health implementers in Kenya [PDF]
Aim: This study examined organizational leadership as a cross-sectoral collaboration factor in the implementation of the One Health (OH) approach using Kenya’s Zoonotic Disease Unit and its core OH implementers as an example.
Thomas Manyibe Nyariki+8 more
doaj +1 more source
Background: Panel reactive antibody (PRA) is a screening test to identify the immunological sensitization of the transplant recipients. The current study focuses on the role of PRA in immunological risk stratification in live donor kidney transplant and ...
Ashwini B Gadde+8 more
doaj +1 more source