Results 61 to 70 of about 584,493 (306)

On the Role of Grain Size and Carbon Content on the Sensitization and Desensitization Behavior of 301 Austenitic Stainless Steel

Metals, 2019
The effect of grain size in the range 72 to 190 μm and carbon content in the range 0.105−0.073 wt.% on the intergranular corrosion of the austenitic stainless steel 301 has been investigated.
Satish Kolli, Vahid Javaheri, Jukka Kömi, David Porter   +3 more
doaj   +1 more source

Thermoluminescence Sensitization of Phyllite Natural Rock

Applied Sciences, 2022
A sensitization procedure is used to enhance the thermoluminescence (TL) sensitivity of phyllite to emit radiation. Phyllite is a type of foliated metamorphic rock made from slate.
Entesar Almogait, Aljawhara H. Almuqrin, Nourah Alhammad, M. I. Sayyed   +3 more
doaj   +1 more source

PreSS/MD: Predictor of Skin Sensitization Caused by Chemicals Leaching from Medical Devices [PDF]

, 2022
Safety evaluation for medical devices includes the toxicity assessment of chemicals used in device manufacturing, cleansing and/or sterilization that may leach into a patient.
Joyce, Borba, Alexander, Tropsha, Diego, Rua, Daniel, Korn, Vinicius, Alves, Eugene, Muratov, Rodolpho, Braga, Nicole, Kleinstreuer, Kevin, Causey   +8 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Transfusion-induced HLA antibodies are short-lived and rarely recur post-heart transplantation: a single-center retrospective study with implications for virtual crossmatching

Frontiers in Immunology
IntroductionThe development of human leukocyte antigen (HLA) antibodies poses a major challenge in transplantation by limiting donor compatibility and increasing the risk of graft failure.
Raja Rajalingam, Stalinraja Maruthamuthu, Brian R. Shy, Julia Cunniffe, David Lowe, Othman A. Aljohani, Georg Wieselthaler   +6 more
doaj   +1 more source

Chronic Pain in the Elderly: Mechanisms and Distinctive Features

Biomolecules, 2021
Background: Chronic pain is a major issue affecting more than 50% of the older population and up to 80% of nursing homes residents. Research on pain in the elderly focuses mainly on the development of clinical tools to assess pain in patients with ...
Andrea Tinnirello, Silvia Mazzoleni, Carola Santi   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Precipitation Behavior and Corrosion Properties of Stirred Zone in FSWed AA5083 Al-Mg Alloy after Sensitization

Metals, 2023
This paper investigated the Mg-rich phase precipitation behavior and the corrosion performance throughout the thickness direction within the stirred zone (SZ) of friction stir welded (FSW) AA5083 alloy after 175 °C/100 h sensitization.
Wenbin Gao, Jiaao Ning, Xiaoyan Gu, Liangyu Chen, Hang Liang, Wenhang Li, John J. Lewandowski   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Grain Boundary Engineering and Its Effect on Intergranular Corrosion Resistance of a Ni-Cr-Mo Based C276 Superalloy

Crystals, 2022
A Ni-Cr-Mo-based C276 superalloy was cold rolled to 5–40% and annealed at 1050 °C for 30 min. The microstructure and grain boundary character distribution after cold rolling and annealing were characterized.
Chi Zhang, Ling Lin, Renchao Chen, Liwen Zhang, Zhiwen Shao   +4 more
doaj   +1 more source