Results 41 to 50 of about 584,493 (306)

Homeostasis of Mitochondrial Ca²⁺ Stores Is Critical for Signal Amplification in Drosophila melanogaster Olfactory Sensory Neurons

Insects, 2022
Insects detect volatile chemosignals with olfactory sensory neurons (OSNs) that express olfactory receptors. Among them, the most sensitive receptors are the odorant receptors (ORs), which form cation channels passing Ca2+.
Eric Wiesel, Sabine Kaltofen, Bill S. Hansson, Dieter Wicher   +3 more
doaj   +1 more source

Atopic sensitization in the first year of life

, 2013
There is conflicting evidence on whether allergen-specific memory is primed prenatally, whether this priming affects persistent immunologic effects, and whether it is modulated by the first environmental exposures in infancy.; We sought to explore the ...
Ege, Markus J, Krauss-Etschmann, S., Pfefferle, P.I., Roduit, Caroline; https://orcid.org/, Braun-Fahrländer, C., Riedler, J., Hirvonen, Maija-Riitta, Weber, J., Ege, Markus J., Pfefferle, Petra I., Dalphin, J.-C., von Mutius, E., Hirvonen, M.R., von Mutius, Erika, Roduit, C., Lauener, R., Kaulek, Vincent, Ege, M.J., Depner, Martin, Roponen, Marjut, Braun-Fahrlaender, Charlotte, Pfefferle, Petra I, Pekkanen, J., Roponen, M., Depner, M., Renseigné, Non, Lauener, Roger, Pasture Study Group,, Dalphin, Jean-Charles, Genuneit, J., Pekkanen, Juha, Krauss-Etschmann, Susanne, Kaulek, V., Riedler, Josef, Roduit, Caroline, Genuneit, Jon, Braun-Fahrländer, Charlotte, Weber, Juliane   +37 more
core   +1 more source

Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens [PDF]

, 2009
BACKGROUND Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due to the existence of possible confounding factors in this type of patients.
Barber, Domingo, Rodriguez, R., Davila, I., Lombardero, M., Salcedo Duran, Gabriel, Colas, C., Torre, F. de la, Villalba, M., Antepara, I., Tabar, I.A., Vidal, C.   +10 more
core   +1 more source

Addiction is a reward deficit and stress surfeit disorder

Frontiers in Psychiatry, 2013
Drug addiction can be defined by a three-stage cycle—binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation—that involves allostatic changes in the brain reward and stress systems.
George F Koob
doaj   +1 more source

Influence of Surface Relief on Orientation of Nematic Liquid Crystals: Polyimide Doped with WS₂ Nanotubes

Crystals, 2022
Among the different methods for orienting liquid crystal (LC) molecules, adding nanoparticles into the matrix of the substrate material towards modifying its surface, is actively pursued.
Natalia Kamanina, Andrey Toikka, Yaroslav Barnash, Alla Zak, Reshef Tenne   +4 more
doaj   +1 more source

Pain‐autonomic interaction: A surrogate marker of central sensitization [PDF]

, 2020
BACKGROUND: Central sensitization represents a key pathophysiological mechanism underlying the development of neuropathic pain, often manifested clinically as mechanical allodynia and hyperalgesia.
Hubli, Michèle, Armin Curt, Paulina S. Scheuren, Scheuren, Paulina S, Curt, Armin, Michèle Hubli, Rosner, Jan, Jan Rosner   +7 more
core   +1 more source

Key requirements for ultraefficient sensitization in hyperfluorescence organic light-emitting diodes

Nature Photonics
Blue organic light-emitting diode (OLED) technology requires further advancements, and hyperfluorescent (HF) OLEDs have emerged as a promising solution to address stability and colour-purity concerns.
K. Stavrou, L. G. Franca, A. Danos, A. Monkman   +3 more
semanticscholar   +1 more source

Non-Animal Methods to Predict Skin Sensitization (II): an assessment of defined approaches

Critical Reviews in Toxicology, 2018
Skin sensitization is a toxicity endpoint of widespread concern, for which the mechanistic understanding and concurrent necessity for non-animal testing approaches have evolved to a critical juncture, with many available options for predicting ...
N. Kleinstreuer, S. Hoffmann, N. Alépée, D. Allen, T. Ashikaga, W. Casey, E. Clouet, M. Cluzel, B. Desprez, N. Gellatly, C. Göbel, P. Kern, M. Klarić, J. Kühnl, S. Martinozzi-Teissier, K. Mewes, M. Miyazawa, J. Strickland, E. van Vliet, Q. Zang, D. Petersohn   +20 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Aero-Allergen Sensitization in the General Population: Longitudinal Analyses of the LEAD (Lung Heart Social Body) Study

Journal of Asthma and Allergy, 2022
Franziska Kölli,1,2 Marie-Kathrin Breyer,2,3 Sylvia Hartl,1– 3 Otto Burghuber,1,2 Emiel FM Wouters,2,4 Torben Sigsgaard,5 Wolfgang Pohl,6 Gabriele Kohlböck,2 Robab Breyer-Kohansal2,3 1Sigmund Freud University, Faculty of Medicine, Vienna, Austria ...
Kölli F, Breyer MK, Hartl S, Burghuber O, Wouters EFM, Sigsgaard T, Pohl W, Kohlböck G, Breyer-Kohansal R   +8 more
doaj