Results 71 to 80 of about 584,493 (306)
, 2011 Respiratory syncytial virus (RSV) bronchiolitis in early life is a risk factor for later development of asthma and atopy. Ribavirin is the only effective drug currently available against acute RSV bronchiolitis.
陳建翰;林于粲;楊曜旭;王麗潔;李志鴻;高全良;江伯倫 +1 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
ChemistryTitanium dioxide (TiO2) thin films sensitized with curcumin were fabricated to investigate the influence of sensitization on their spectroscopic, optical, and photocatalytic properties. TiO2 films were prepared using different curcumin concentrations and
William Vallejo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
BiomedicinesBackground: Since the discovery of successful direct-acting antiviral (DAA) treatment, kidneys from hepatitis C virus (HCV) RNA-positive donors represent a new opportunity to expand the organ donor pool for HCV-negative recipients.
Tanja Belčič Mikič +3 more
doaj +1 more source
Brain mechanisms of short-term habituation and sensitization towards dyspnea
Frontiers in Psychology, 2015 Dyspnea is a prevalent and threatening cardinal symptom in many diseases including asthma. Whether patients suffering from dyspnea show habituation or sensitization towards repeated experiences of dyspnea is relevant for both quality of life and ...
M Cornelia Stoeckel +5 more
doaj +1 more source
Specific Immunotherapy in a Murine Model of Grass Pollen (Phl p5b)-Induced Airway Inflammation
Frontiers in Allergy, 2021 Background: The use of ovalbumin as a model allergen in murine models of allergic asthma is controversially discussed since it is not an aeroallergen and sensitization can only be achieved by using strong Th2-inducing adjuvants. Therefore, in this study,
Matthias Stiehm, Marcus Peters
doaj +1 more source
Microglial TNFα suppresses cocaine-induced plasticity and behavioral sensitization
Neuron, 2016 Summary Repeated administration of cocaine results in the development of behavioral sensitization, accompanied by a decrease in excitatory synaptic strength in the nucleus accumbens (NAc) through an unknown mechanism.
G. Lewitus +5 more
semanticscholar +1 more source
The importance of central sensitization for clinical trials of Disease Modifying Osteoarthritis drugs (DMOADs) [PDF]
Osteoarthritis (OA) pain is associated with structural changes in the joint, which are usually quantified by imaging techniques. It is anticipated that structural disease modifying OA drugs (DMOADs) would reduce the burden of OA pain.
McWilliams, Daniel F, Walsh, David A
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source