Results 191 to 200 of about 91,363 (358)

Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation. [PDF]

PLoS Biol
Lee YS.
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

When two signals are better than one: Synergistic control of erythropoiesis. [PDF]

PLoS Biol
Wilson NK.
europepmc   +1 more source

Comprehensive approach for correction of motion and distortion in diffusion‐weighted MRI

Magnetic Resonance in Medicine, 2004
G. Rohde, G. Rohde, A. Barnett, P. Basser, S. Marenco, C. Pierpaoli   +5 more
semanticscholar   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Tetramethylol acetylenediurea: MAK Value Documentation - Translation of the German version from 2023. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission https://www.dfg.de/de/ueber-uns/gremien/senat/arbeitsstoffe/mitglieder.   +1 more
europepmc   +1 more source

The Sensitive Body: corporeality and affectivity in Merleau‑Ponty

Revista Filosófica de Coimbra
In this study, we seek to interrogate and delve into the enigma of the sensitive body conceiving affectivity as the foundational way of being in the world in Merleau‑Ponty’s philosophy. Our study aims to demonstrate that the flesh acts as the in‑between (“entre‑deux”) of the sensitive body, which we term the affective‑lived body (affective‑bodily ...
openaire   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, EarlyView.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

Insulin Resistance/Hyperinsulinemia Should Be Considered in the Prevention and Treatment of Essential Hypertension. [PDF]

Biomedicines
Fazio S, Affuso F.
europepmc   +1 more source

Telemetering from within the body using a pressure-sensitive radio pill [PDF]

Gut, 1962
B W, WATSON, B, ROSS, A W, KAY
openaire   +2 more sources