Results 91 to 100 of about 29,118 (259)

Quadrotor Accelerometer and Gyroscope Sensor Fault Diagnosis Using Nonlinear Adaptive Estimation Methods

International Journal of Prognostics and Health Management, 2016
This paper presents the design, analysis, and real-time experimental evaluation results of a nonlinear sensor fault diagnosis scheme for quadrotor unmanned air vehicles (UAV).
Remus Avram, Xiaodong Zhang, Jonathan Muse   +2 more
doaj   +1 more source

The Real-time Implementation of Envelope Analysis for Bearing Fault Diagnosis based on Wireless Sensor Network

, 2013
-Wireless sensor network (WSN) is gaining popularity in condition monitoring (CM) fields. However, enormous datasets obtained by data acquisition systems with high sampling rate cannot be transmitted effectively via a WSN due to its limited transmission ...
Gu, Fengshou, Mustafa, A., Ball, Andrew, Zhen, Dong, Ball, A. D., Gu, F., Zhen, D., Gu, J. X., Gu, J.X., Feng, G.   +9 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Real-Time Fault Diagnosis for Hydraulic System Based on Multi-Sensor Convolutional Neural Network

Sensors
This paper proposed a real-time fault diagnostic method for hydraulic systems using data collected from multiple sensors. The method is based on a proposed multi-sensor convolutional neural network (MS-CNN) that incorporates feature extraction, sensor ...
Haohan Tao, Peng Jia, Xiangyu Wang, Liquan Wang   +3 more
doaj   +1 more source

Wireless sensor network control through statistical methods

, 2015
Wireless Sensor Networks (WSNs) form a new paradigm of computing that allows the physical world to be measured at an unprecedented resolution; and the importance of the technology has been increasingly recognised.
Fang, Lei
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Rough set based gas turbine fault isolation study [PDF]

, 2010
Gas path fault isolation is one of the key techniques in Engine Health Management systems. In order to accomplish gas path fault isolation successfully for a gas turbine engine, both an accurate off-design performance model and an effective fault ...
Wang, Lihui.
core