Results 111 to 120 of about 153,439 (296)

Model Selection Approach for Distributed Fault Detection in Wireless Sensor Networks

open access: yes, 2013
Sensor networks aim at monitoring their surroundings for event detection and object tracking. But, due to failure, or death of sensors, false signal can be transmitted.
Dewanji, Anup   +3 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Research on Fault Analysis and Fault-Tolerant Control of EV/HEV Powertrain

open access: yes, 2014
International audienceThis paper presents research works in the topics of fault analysis and fault tolerant control of an electric vehicle powered by an inverter-fed induction motor drive and the usual sensors.
Benbouzid, Mohamed   +4 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Implementing fault-tolerant sensors [PDF]

open access: yes
One aspect of fault tolerance in process control programs is the ability to tolerate sensor failure. A methodology is presented for transforming a process control program that cannot tolerate sensor failures to one that can.
Marzullo, Keith
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Online Fault-Tolerant Onboard Aeroengine Model Tuning Structure

open access: yesInternational Journal of Aerospace Engineering, 2016
Online onboard aeroengine models (OBEMs) have been widely used in health management, fault diagnostics, and fault-tolerant control. A mismatch between the OBEM and the actual engine may be caused by a variety of factors such as health degradation or ...
Shuiting Ding   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Actuator Fault Diagnosis with Robustness to Sensor Distortion

open access: yesJournal of Control Science and Engineering, 2008
Actuator fault diagnosis is often studied under strong assumptions on available sensors. Typically, it is assumed that the sensors are either fault free or sufficiently redundant.
Qinghua Zhang
doaj   +1 more source

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