Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Fault-tolerant system considerations for a redundant strapdown inertial measurement unit [PDF]
The development and evaluation of a fault-tolerant system for the Redundant Strapdown Inertial Measurement Unit (RSDIMU) being developed and evaluated by the NASA Langley Research Center was continued.
Mangoubi, R., Motyka, P., Ornedo, R.
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Fault diagnosis method for redundancy sensors of electric actuator
Xibei Gongye Daxue XuebaoIn order to solve the singular fault modes of redundant position sensors in electric actuators, a fault diagnosis method based on Hall sensor analytical model is proposed on the basis of traditional redundancy comparison algorithm.
CUI Yuwei, LI Aijun, SUN Yang
doaj +1 more source
Engine fault diagnosis based on sensor data fusion using evidence theory
Advances in Mechanical Engineering, 2016 Evidence theory is widely used in fault diagnosis due to its efficiency to model and fuse sensor data. However, one shortcoming of the existing evidential fault diagnosis methods is that only the basic probability assignments in singletons can be ...
Moxian Song, Wen Jiang
doaj +1 more source
Decentralized Sensor Fault-Tolerant Control of DC Microgrids Using the Attracting Ellipsoid Method. [PDF]
Sensors (Basel), 2023 Soliman HM +3 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Application of RBF Neural Network to Locomotive Speed Sensor Fault Diagnosis
机车电传动, 2012 An locomotive speed sensor fault diagnosis method based on Radial Basis Function (RBF) neural network was presented. RBF neural network predictor was built by taking common faults of photoelectric speed sensor as model.
XIE Bin, LI Guo-ning, FENG Tao, LI Bo
doaj
Spatial Domain Image Fusion with Particle Swarm Optimization and Lightweight AlexNet for Robotic Fish Sensor Fault Diagnosis. [PDF]
Biomimetics (Basel), 2023 Fan X, Deng S, Wu Z, Fan J, Zhou C.
europepmc +1 more source
Machine learning techniques for fault isolation and sensor placement [PDF]
Fault isolation and sensor placement are vital for monitoring and diagnosis. A sensor conveys information about a system's state that guides troubleshooting if problems arise.
Carnes, James R., Fisher, Douglas H.
core +1 more source