Results 101 to 110 of about 153,439 (296)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Anomaly Detection and Removal Using Non-Stationary Gaussian Processes

open access: yes, 2015
This paper proposes a novel Gaussian process approach to fault removal in time-series data. Fault removal does not delete the faulty signal data but, instead, massages the fault from the data.
Garnett, Roman   +3 more
core  

Integrated Inertial/gps [PDF]

open access: yes, 1990
The presence of failures in navigation sensors can cause the determination of an erroneous aircraft state estimate, which includes position, attitude, and their derivatives.
Kline, Paul, Vangraas, Frank
core   +1 more source

Sensors and Fault Diagnostics in Power System

open access: yesSensors
The adequate technical condition assessment of key apparatuses is a crucial assumption in the delivery of reliable and continuous electric power to customers [...]
Michal Kunicki   +2 more
openaire   +3 more sources

NONLINEAR SYSTEM SENSOR FAULT ESTIMATION

open access: yesIFAC Proceedings Volumes, 2005
Based on the techniques of high gain observer and adaptive estimation,an algorithm is proposed in this paper for sensor fault estimationin nonlinear systems. It is essentially assumed that a high gainobserver exists for the fault-free system. A high gainadaptive observer is then designed for sensor fault estimation.The convergence of the algorithm is ...
Zhang, Qinghua, Besancon, Gildas
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A Fault Tolerant System for an Integrated Avionics Sensor Configuration [PDF]

open access: yes
An aircraft sensor fault tolerant system methodology for the Transport Systems Research Vehicle in a Microwave Landing System (MLS) environment is described.
Caglayan, A. K., Lancraft, R. E.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Real-Time Fault Diagnosis for Hydraulic System Based on Multi-Sensor Convolutional Neural Network

open access: yesSensors
This paper proposed a real-time fault diagnostic method for hydraulic systems using data collected from multiple sensors. The method is based on a proposed multi-sensor convolutional neural network (MS-CNN) that incorporates feature extraction, sensor ...
Haohan Tao   +3 more
doaj   +1 more source

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