Results 131 to 140 of about 153,439 (296)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Gearbox fault diagnosis under different operating conditions based on time synchronous average and ensemble empirical mode decomposition [PDF]
, 2009 In this paper, a new method is proposed by combining ensemble empirical mode decomposition (EEMD) with order tracking techniques to analyse the vibration signals from a two stage helical gearbox.
Ball, A +4 more
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Fuzzy Echo State Network-Based Fault Diagnosis of Remote-Controlled Robotic Arms
Applied SciencesThis paper presents a novel fault diagnosis technique for remote-controlled robotic arm systems, utilizing deep fuzzy echo state networks (DFESNs) and applies the covariance matrix adaptation evolution strategy (CMA-ES) to optimize the hyperparameters of
Shurong Peng +4 more
doaj +1 more source
A Novel Adaptive Sensor Fault Estimation Algorithm in Robust Fault Diagnosis. [PDF]
Sensors (Basel), 2022 Pazera M, Witczak M.
europepmc +1 more source
Sensor placement for fault detection and localization
, 2008 Abstract A general approach is proposed for designing the cheapest sensor network able to detect and locate a set of specified faults. The method is based on the sensitivity of process residuals with respect to faults. A genetic algorithm is used to select the sensors and their locations. Results are shown for two water networks.
Gerkens, Carine, Heyen, Georges
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Multi-Sensor Fault Diagnosis Based on Time Series in an Intelligent Mechanical System. [PDF]
Sensors (Basel), 2022 Xu Z, Li Q, Qian L, Wang M.
europepmc +1 more source