Results 141 to 150 of about 29,118 (259)

Enhanced Multiscale Principal Component Analysis for Improved Sensor Fault Detection and Isolation. [PDF]

Sensors (Basel), 2022
Malluhi B, Nounou H, Nounou M.
europepmc   +1 more source

A general formulation for fault detection in stochastic continuous-time dynamical systems

, 2008
In this work, a general formulation for fault detection in stochastic continuoustime dynamical systems is presented. This formulation is based on the definition of a pre-Hilbert space so that orthogonal projection techniques, based on the statistics of ...
Zufiria Zatarain, Pedro José
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Sensor Fault-Tolerant Control of Microgrid Using Robust Sliding-Mode Observer. [PDF]

Sensors (Basel), 2022
Shahzad E, Khan AU, Iqbal M, Saeed A, Hafeez G, Waseem A, Albogamy FR, Ullah Z.   +7 more
europepmc   +1 more source

Hibadetektálás korszerű analitikus módszerei járműipari alkalmazásokkal = Advanced analytic methods to fault detection with application to vehicle systems

, 2009
1) A rendszer modelljének invertálásán alapuló detektálószűrők tulajdonságainak kutatása során kapott eredmények, ideértve elsősorban az inverz geometriai tulajdonságait és az inverz dinamika előállítására vonatkozó módszereket, lehetővé tették az ...
Edelmayer, András, Fazekas, Zoltán, Szabó, Zoltán, Nádai, László, Soumelidis, Alexandros   +4 more
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

High Precision Feature Fast Extraction Strategy for Aircraft Attitude Sensor Fault Based on RepVGG and SENet Attention Mechanism. [PDF]

Sensors (Basel), 2022
Jia Z, Wang K, Li Y, Liu Z, Qin J, Yang Q.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Sensor Fault Diagnosis Using a Machine Fuzzy Lyapunov-Based Computed Ratio Algorithm. [PDF]

Sensors (Basel), 2022
TayebiHaghighi S, Koo I.
europepmc   +1 more source