Results 121 to 130 of about 18,846 (144)
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Homology modelling of a sensor histidine kinase from Aeromonas hydrophila
Journal of Molecular Modeling, 2009Aeromonas hydrophila has been implicated in extra-intestinal infection and diarrhoea in humans. Targetting unique effectors of bacterial pathogens is considered a powerful strategy for drug design against bacterial variations to drug resistance. The two-component bacterial system involving sensor histidine kinase (SHK) and its response regulators is ...
Mobashar Hussain Urf Turabe, Fazil +4 more
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Biochimica Et Biophysica Acta - Proteins and Proteomics, 2003
To explore the functional mechanism of inter-domain interaction in a sensor histidine kinase, five chimeric sensory kinases were constructed. In each of these chimeric proteins (CskA254, CskA264, CskA274, CskA284, and CskA294), the sensor domain of heme-based O(2) sensor FixL, obtained from Sinorhizobium meliloti, was fused with the histidine kinase ...
Yoshitsugu Shiro
exaly +3 more sources
To explore the functional mechanism of inter-domain interaction in a sensor histidine kinase, five chimeric sensory kinases were constructed. In each of these chimeric proteins (CskA254, CskA264, CskA274, CskA284, and CskA294), the sensor domain of heme-based O(2) sensor FixL, obtained from Sinorhizobium meliloti, was fused with the histidine kinase ...
Yoshitsugu Shiro
exaly +3 more sources
Sensor histidine kinases mediate ABA and osmostress signaling in the moss Physcomitrium patens
Current Biology, 2022To survive fluctuating water availability on land, terrestrial plants must be able to sense water stresses, such as drought and flooding. The plant hormone abscisic acid (ABA) and plant-specific SNF1-related protein kinase 2 (SnRK2) play key roles in plant osmostress responses.
Tsukasa Toriyama +13 more
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Structure and distribution of sensor histidine kinases in the fungal kingdom
Current GeneticsTwo-component systems (TCSs) are diverse cell signaling pathways that play a significant role in coping with a wide range of environmental cues in both prokaryotic and eukaryotic organisms. These transduction circuitries are primarily governed by histidine kinases (HKs), which act as sensing proteins of a broad variety of stressors.
Mina, Sara +5 more
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Characterization of the sensor domain of QseE histidine kinase from Escherichia coli
Protein Expression and Purification, 2016In enterohemorrhagic Escherichia coli (EHEC), the QseEF two-component system causes attaching and effacing (AE) lesion on epithelial cells. QseE histidine kinase senses the host hormone epinephrine, sulfate, and phosphate; it also regulates QseF response regulator, which activates LEE gene that encodes AE lesion.
Kwon Joo, Yeo +5 more
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Two L-histidine transporters and one sensor kinase
2022The Gram-negative soil bacterium Pseudomonas putida KT2440 colonizes the rhizosphere of plants and promotes their growth. It is genetically accessible, solvent-resistant and biosafe and therefore, serves as a platform for industrial biosyntheses (for example, plastic-like polymers and biosurfactants).
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Blue-Light-Activated Histidine Kinases: Two-Component Sensors in Bacteria
Science, 2007Histidine kinases, used for environmental sensing by bacterial two-component systems, are involved in regulation of bacterial gene expression, chemotaxis, phototaxis, and virulence. Flavin-containing domains function as light-sensory modules in plant and algal phototropins and in fungal blue-light receptors. We have discovered that
Trevor E, Swartz +12 more
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The Regulation of Histidine Sensor Kinase Complexes by Quorum Sensing Signal Molecules
2007Two-component sensor kinase signaling systems are widespread in bacteria, but gaining mechanistic insight into how kinase activity is controlled by ligand binding has proved challenging. Here, we discuss this problem in the context of our structural and functional studies of bacterial quorum sensing receptors.
Matthew B, Neiditch +1 more
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Bacterial Assay to Study Plant Sensor Histidine Kinases
2011Cytokinins, like other phytohormones, act in plants as signaling molecules at very low concentrations. The system that mediates between their chemical recognition and the responses that they induce requires a hormone receptor that, together with down-stream located elements, forms a signaling network, converting the signal into a specific response ...
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Molecular Genetics and Genomics, 2003
Embryo sac formation is a fundamental step in sexual reproduction in plants. However, the key players involved in the development of the female gametophyte remain elusive. We present data indicating that a two-component sensor histidine kinase, CKI1, originally implicated in cytokinin perception, is required for completion of megagametogenesis in ...
Hejátko, Jan +4 more
openaire +3 more sources
Embryo sac formation is a fundamental step in sexual reproduction in plants. However, the key players involved in the development of the female gametophyte remain elusive. We present data indicating that a two-component sensor histidine kinase, CKI1, originally implicated in cytokinin perception, is required for completion of megagametogenesis in ...
Hejátko, Jan +4 more
openaire +3 more sources