Results 51 to 60 of about 217,477 (293)

Sistema de adquisicion y explotacion de datos basado en una red de sensores IEEE802.15.4 [PDF]

open access: yes, 2011
Este proyecto tiene como objetivo poder realizar la monitorizacion de diversas zonas, a escoger por el usuario, mediante una red de sensores. Para realizar esta monitorizacion, en primer lugar se distribuiran los sensores, formando una red que realice ...
Caballero Trullenque, Eduardo   +1 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Aplicaciones y tecnologías para el desarrollo de la internet de las cosas

open access: yesRevista Metropolitana de Ciencias Aplicadas, 2018
En la actualidad existe una gran cantidad de equipos conectados a internet que generan datos y suministran información para determinados procesos que facilitan la vida de los seres humanos.
Romel Vázquez Rodríguez
doaj   +1 more source

Validación experimental de un modelo de músculo activado de forma artificial [PDF]

open access: yes, 2014
Postprint (published ...
Alonso, Francisco Javier   +5 more
core  

Architectural perspectives in the cathedral of Palermo : image-based modeling for cultural heritage understanding and enhancement [PDF]

open access: yes, 2015
Palermo off ers a repertoire of both artistic and architectural solid perspective of great beauty and in large quantity. This paper addresses the problem of the 3D survey of these works and their related study through the use of image-based modelling
Inzerillo, Laura, Santagati, Cettina
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Instrumentation for mechanical vibrations analysis in the time domain and frequency domain using the Arduino platform

open access: yesRevista Brasileira de Ensino de Física
In this paper, we use the Arduino platform together with sensors as accelerometer, gyroscope and ultrasound, to measure vibrations in mechanical systems.
Marcus Varanis   +3 more
doaj   +1 more source

Strain monitoring of tapestries: results of a three-year research project [PDF]

open access: yes, 2012
The outcomes of an interdisciplinary research project between conservators and engineers investigating the strain experienced by different areas of a tapestry are described. Two techniques were used: full-field monitoring using digital image correlation (
Chambers, A.   +6 more
core  

Aptamer Sensors [PDF]

open access: yesBiosensors, 2017
In the last years, great progress has been accomplished in the development of aptamer sensors with different transducers. In order to improve the sensitivity of these biosensors, several methodologies have been employed. In this Special Issue, the state of art and the future trends in the field of aptamer sensors have been explored.
openaire   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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