Results 51 to 60 of about 218,605 (292)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Revista Brasileira de Ensino de FísicaIn this paper, we use the Arduino platform together with sensors as accelerometer, gyroscope and ultrasound, to measure vibrations in mechanical systems.
Marcus Varanis +3 more
doaj +1 more source
Sistema distribuído de monitorização de consumos e de qualidade de energia elétrica [PDF]
, 2012 Este artigo descreve a implementação e teste de um sistema distribuído de medição de grandezas elétricas, concebido para utilização com cargas tipicamente existentes nas residências, que possibilita a monitorização remota do consumo e também possui ...
Afonso, José A. +2 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Biosensors, 2017 In the last years, great progress has been accomplished in the development of aptamer sensors with different transducers. In order to improve the sensitivity of these biosensors, several methodologies have been employed. In this Special Issue, the state of art and the future trends in the field of aptamer sensors have been explored.
openaire +4 more sources
Validación experimental de un modelo de músculo activado de forma artificial [PDF]
, 2014 Postprint (published ...
Alonso, Francisco Javier +5 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Strain monitoring of tapestries: results of a three-year research project [PDF]
, 2012 The outcomes of an interdisciplinary research project between conservators and engineers investigating the strain experienced by different areas of a tapestry are described. Two techniques were used: full-field monitoring using digital image correlation (
Chambers, A. +6 more
core
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Physical Sensors: Thermal Sensors
, 2023 Thermal sensors have been intensively developed and used in a wide range of applications from monitoring of industrial processes to environmental control. Thermal sensors are capable of measuring various thermal signals such as temperature, flow, acceleration and angular velocity.
Dinh, Toan +5 more
openaire +2 more sources