Results 41 to 50 of about 793,712 (293)
In the current investigation, the potential utility of cinnamaldehyde obtained from cinnamon (Cinnamomum zeylanicum) bark powder in enhancing the antioxidant capacity of dark chocolates was evaluated.
Muhammad Ahmar JAHANGIR +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Sensorial Organization as an Ethics of Space: Digital Media in Everyday Life
This article outlines an analysis of the ethical organization of digital media and social and individual space in everyday life. This is made from a perspective of an ‘ethics of the ordinary’, highlighting the mundane negotiations and practices conducted
Stina Bengtsson
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Croquages de langue en formation d’enseignants
Le sensoriel et l’expression plastique sont-ils des outils de formation pertinents pour aller à la rencontre de l’altérité et de la diversité linguistique et culturelle ?
Annemarie Dinvaut
doaj
El sonido y sus múltiples resonancias. Tres proyectos
Numerosos estudios en las últimas décadas muestran cómo el sonido es un importante elemento capaz de proporcionar nuevos conocimientos sobre el entorno y sobre las relaciones entre el ser humano y el medio.
Cristina Palmese, José Luis Carles
doaj +1 more source

