Results 111 to 120 of about 27,096,978 (348)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Drink Red: Phenolic Composition of Red Fruit Juices and Their Sensorial Acceptance

Beverages, 2016
Consumers’ food quality perception and sensorial experience are important in food consumption behavior and food choice. Red fruit juices are appreciated fruit juices for almost all consumers, due to their flavor and intense red color.
Alice Vilela, Fernanda Cosme
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The Teaching of Vocabulary through the Multisensory Approach to EFL Third Age Adults in a Public Nursing Home in Pereira, Colombia [PDF]

, 2019
El aprendizaje del idioma inglés es un proceso que conlleva beneficios cognitivos, personales, sociales y de crecimiento. Esta investigación cualitativa tuvo como objetivo integrar a una población de adultos mayores en lecciones de vocabulario en inglés ...
Largo Gonzáles, Juan Camilo, Rojas Rodríguez, Luisa María, Valencia Parra, Alejandro   +2 more
core  

‘Artificial Sensory Analysis’ for Sensory Classification of Prosecco Sparkling Wines

Chemical Engineering Transactions, 2015
Real-time in-process reference to a consolidated standard during sparkling wine production would be beneficial for reducing product loss and/or allowing a timely diagnosis of intervention needs (correction etc). Instead, end-point control by assaying by the oenologist supervising batch production is the only form of (sensory) control normally carried ...
FRANCESCHI, DEBORAH, Tiranno, Marco, VINCENZI, SIMONE, BOATTO, VASCO LADISLAO, BRAVI, MARCO   +4 more
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Informational Mode of the Brain Operation and Consciousness as an Informational Related System [PDF]

, 2019
Introduction: the objective of the investigation is to analyse the informational operating-mode of the brain and to extract conclusions on the structure of the informational system of the human body and consciousness.
Gaiseanu, Florin
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The evolution of representation in simple cognitive networks [PDF]

, 2013
Representations are internal models of the environment that can provide guidance to a behaving agent, even in the absence of sensory information. It is not clear how representations are developed and whether or not they are necessary or even essential ...
Arend Hintze, Beer R., Chomsky N., Christoph Adami, Cohen H., Craik K., Fodor J., Harnad S., Haugeland J., Hawkins J., Johnson-Laird P., Koller D., Lars Marstaller, Marr D., Moravec H. P., Newell A., Nolfi S., Orr H., Phillipps W. A., Pinker S., Pitt D.   +20 more
core   +2 more sources