Results 71 to 80 of about 47,561 (284)

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

Developmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel, Maya Silver, Aaron H. Wasserman, Samantha Rea, Charles C. Hong, Charles H. Williams   +5 more
wiley   +1 more source

A Novel PTRH2 Gene Mutation Causing Infantile-onset Multisystem Neurologic, Endocrine, and Pancreatic Disease in a Bahraini Patient

Oman Medical Journal
Infantile-onset multisystem neurologic, endocrine, and pancreatic disease (IMNEPD) is a rare autosomal recessive multisystemic disease with a prevalence of < 1/1 000 000.
Hasan M. Isa, Sara D. Khalaf, Sara Janahi, Mohamed M. Naser, Noor Al Hamad, Hasan Alhaddar, Maryam Busehail   +6 more
doaj   +1 more source

Effect of Sensorineural Damage upon the Cat's Intensity-Difference Threshold [PDF]

, 1964
Donald N. Elliott
openalex   +1 more source

Protective Effects of Buckwheat and Isoquercitrin Against Noise‐Induced Hearing Loss in Mice: An Antioxidant Strategy Targeting the Nrf2/HO‐1 Pathway in Auditory Hair Cells

Food Frontiers, EarlyView.
Isoquercitrin (IQ), a major bioactive compound in buckwheat (Fagopyrum esculentum Moench; BW), serves as a key mediator of the protective effects of BW against noise‐induced hearing loss (NIHL) by activating the Nrf2/HO‐1 signaling pathway, and oral administration of BW and IQ significantly attenuates oxidative stress and hair cell apoptosis through ...
Hojin Lee, Gahwa Jung, Guijae Yoo, Jonghoon Jung, Jae‐Yong Park, Changho Lee, Jaekwang Lee   +6 more
wiley   +1 more source

The Effect of Rivaroxaban in the Complementary Therapy of Sudden Sensorineural Hearing Loss

Advanced Biomedical Research
Background: Due to the importance of sudden sensorineural hearing loss (SSNHL) and the possible role of blood coagulation in its mechanism and the likely therapeutic effect of anticoagulants and also the lack of studies in this field, this study aimed to
Mehrdad Rogha, Ehsan Moshtaghi
doaj   +1 more source

Comparing Tinnitus Suppression in Asymmetric Hearing Loss and Single‐Sided Deafness: Cochlear Versus Bone Conduction Implants

The Laryngoscope, EarlyView.
While both cochlear implants and bone conduction implants improve tinnitus symptoms, cochlear implants provide significantly greater suppression across multiple tinnitus severity measures and a higher cure rate, positioning it as the preferred option for tinnitus management in asymmetric hearing loss and single‐sided deafness patients.
Jae Sang Han, Min Chae Jeon, Chan Mi Lee, Gianfranco C. Velasco, So Young Park, Shi Nae Park   +5 more
wiley   +1 more source

Clinical Genetic Testing for Hearing Loss: Implications for Genetic Counseling and Gene-Based Therapies

Biomedicines
Genetic factors contribute significantly to congenital hearing loss, with non-syndromic cases being more prevalent and genetically heterogeneous. Currently, 150 genes have been associated with non-syndromic hearing loss, and their identification has ...
Nam K. Lee, Kristin M. Uhler, Patricia J. Yoon, Regie Lyn P. Santos-Cortez   +3 more
doaj   +1 more source

Congenital Rubella and CNS Defects

Pediatric Neurology Briefs, 1987
The University Department of Pediatrics and Child Health, Leeds, and the Department of Microbiology, Hospital for Sick Children, London, collaborated in a study of the time relations between maternal rubella infection in pregnancy and the presence and ...
J Gordon Millichap
doaj   +1 more source

The relationship between speech discrimination ability and self-assessed hearing-handicap of adults with sensorineural hearing losses as a function of reverberation and noise [PDF]

, 1976
David Mason, C. W.
openalex   +1 more source

Long‐Term Outcomes of Adult Temporal Bone Fractures With Hearing Loss: Results of a Multinational Database Analysis

The Laryngoscope, EarlyView.
This study uses a large multinational database to examine long‐term outcomes of adult temporal bone fractures. The risk for meningitis, labyrinthitis, facial nerve disorders, and cerebrospinal fluid leaks was elevated after fracture. Cochlear implantation was also more likely after temporal bone fracture.
Jason L. Steele, Heather J. Smith, Samira Takkoush, Jumah G. Ahmad, Zachary D. Urdang, Neil S. Patel, Richard K. Gurgel, Mana Espahbodi   +7 more
wiley   +1 more source