Results 171 to 180 of about 80,496 (333)

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

Cell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang, Hairong Xiao, Jiheng Wu, Yanqin Lin, Yiheng Ao, Zixuan Ye, Xin Tan, Fanliang Kong, Xin Chen, Renjie Chai, Shasha Zhang   +10 more
wiley   +1 more source

Treatment of Sudden Sensorineural Hearing Loss

, 1978
Kiyotaka Murata
openalex   +2 more sources

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

Epilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti, Alessio Passalacqua, Maria Cristina Regondi, Giada D'Ambrosio, Alessandra Morano, Michele Romoli, Giulia Maira, Flavio Villani, Pietro Mattioli, Diego Franciotta, Andrea Stabile, Marco de Curtis, Matteo Gastaldi, Francesco Deleo, Laura Librizzi   +14 more
wiley   +1 more source

Otitis media and congenital perilymphatic fistula as a cause of sensorineural hearing loss in children

, 1988
Charles D. Bluestone
openalex   +1 more source

Hearing Threshold Estimation With Distortion Product Otoacoustic Emission Growth Functions in People With Intellectual Disabilities in an Outreach Setting

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with intellectual disabilities often have undetected hearing loss. Methods In this prospective observational study featuring 110 adults with intellectual disabilities, hearing evaluations based on objective hearing threshold estimation using distortion‐product otoacoustic emission growth functions (DPOAEgfs) were performed in
Eleftherios Savvas, Emmanouela Dimitrakopoulou, Harald A. Euler, Frans Coninx, Felix Bluemel, Anne Krieger, Karolin Schaefer, Philipp Mathmann, Corinna Gietmann, Katrin Neumann   +9 more
wiley   +1 more source

The cochlear apex demystified: Implications from synchrotron radiation phase‐contrast imaging and microscopy for cochlear implantation

Journal of Anatomy, EarlyView.
This study is the first to present the detailed cellular organization and three‐dimensional (3D) tonotopic arrangement of the human organ of Corti, spiral ganglion, and central modiolus using synchrotron radiation phase‐contrast imaging (SR‐PCI) with matched histological cross‐sections.
Hao Li, Rudolf Glueckert, Anneliese Schrott‐Fischer, Karin Staxäng, Hanif M. Ladak, Helge Rask‐Andersen, Sumit Agrawal   +6 more
wiley   +1 more source

Risk Factors of Sensorineural Hearing Loss in Preterm Infants [PDF]

, 1997
D Anagnostakis, J. Messaritakis, Helen Mandyla   +2 more
openalex   +1 more source

The relationship between maternal periodontitis and congenital cytomegalovirus: A hypothetical model and therapeutic implications

Periodontology 2000, EarlyView.
Abstract Background The primary goal of periodontology is to prevent tooth loss and reduce the risk of focal infections. Periodontitis lesions can harbor hundreds of thousands of active cytomegaloviruses (virions), which can easily enter the systemic circulation and potentially infect the fetus of a mother with compromised immunity.
Jørgen Slots
wiley   +1 more source

Eleven cases of aortitis syndrome with sensorineural hearing loss.

, 1989
Katsuhide Inagi, Tetsuya Shitara, Makito Okamoto, Kouji Tokumasu, Akito Fujino, Toyota Ishii, Toshihiko Kamata   +6 more
openalex   +2 more sources

Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest

Experimental Physiology, EarlyView.
Abstract Modulation of bone marrow adipose tissue (BMAT) with prolonged inactivity was reported in haemopoietic but not in non‐haemopoietic bones. This prospective randomized controlled trial submitted 16 men and 8 women to 60 days of 6° head‐down‐tilt bed rest.
Tammy Liu, Gerd Melkus, Tim Ramsay, Alain Berthiaume, Gabriele Armbrecht, Guy Trudel   +5 more
wiley   +1 more source