Results 101 to 110 of about 2,538,180 (361)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis

Arthritis Research & Therapy
Background Studying pain in rodent models of arthritis is challenging. For example, assessing functional changes in joint neurons is challenging due to their relative scarcity amongst all sensory neurons.
George L. Goodwin, Alina-Cristina Marin, Julia Vlachaki Walker, Carl Hobbs, Franziska Denk   +4 more
doaj   +1 more source

Neuronal Pathways and Synaptic Connexions in the Abdominal Cord of the Crayfish [PDF]

, 1959
1. An investigation has been made into the function and distribution of nerve fibres in the abdominal ganglion chain and its roots in the crayfish, Procambarus clarkii, by leading off action potentials from small prepared bundles following sensory ...
Hughes, G. M., Wiersma, C. A. G.
core   +1 more source

An Inversion Disrupting FAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed [PDF]

, 2016
Sensory neuropathy in the Border Collie is a severe neurological disorder caused by the degeneration of sensory and, to a lesser extent, motor nerve cells with clinical signs starting between 2 and 7 months of age.
Beltran, E, De Risio, L, Forman, O P, Gutierrez-Quintana, R, Hitti, R J, Jenkins, C A, Mellersh, C, O'Brien, D P, Pettitt, L, Shelton, G D   +9 more
core   +4 more sources

Coexisting representations of sensory and mnemonic information in human visual cortex

Nature Neuroscience, 2019
Traversing sensory environments requires keeping relevant information in mind while simultaneously processing new inputs. Visual information is kept in working memory via feature-selective responses in early visual cortex, but recent work has suggested ...
R. Rademaker, C. Chunharas, J. Serences
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

An Artificial Sensory Neuron with Tactile Perceptual Learning

Advances in Materials, 2018
Sensory neurons within skin form an interface between the external physical reality and the inner tactile perception. This interface enables sensory information to be organized identified, and interpreted through perceptual learning—the process whereby ...
Changjin Wan, Geng Chen, Y. Fu, Ming Wang, N. Matsuhisa, Shaowu Pan, Liang Pan, H. Yang, Qing Wan, Liqiang Zhu, Xiaodong Chen   +10 more
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Interior maps in posterior pareital cortex [PDF]

, 2002
The posterior parietal cortex (PPC), historically believed to be a sensory structure, is now viewed as an area important for sensory-motor integration.
Andersen, Richard A., Bueno, Christopher A.   +1 more
core   +1 more source

Role of sufficient statistics in stochastic thermodynamics and its implication to sensory adaptation

, 2018
A sufficient statistic is a significant concept in statistics, which means a probability variable that has sufficient information required for an inference task.
Matsumoto, Takumi, Sagawa, Takahiro
core   +1 more source