Results 121 to 130 of about 1,103,473 (317)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Proliferation-dependent adipogenic differentiation of progenitor cells in rat coronary artery explants

Stem Cell Research & Therapy
Background Lipid accumulation is involved in pathogenesis of cardiovascular disease. Progenitor cells are associated with the disease progression; however, their identity remains unclear.
Spyridoula Kazantzi, Philip Victor Reducha, Kristian A. Haanes   +2 more
doaj   +1 more source

Sensory Systems

, 2007
false ; 2016-03-16T23:02 ...
unknown ( host institution ), Sokolowski, B.H.A ( author )   +1 more
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Seminar: sensory stories retold

The Sensory Stories Retold seminar showcased the first year of the Sensory Objects project, which was based at Speke Hall, a National Trust house in Liverpool.
Minnion, Andy, Hwang, Faustina, Hollinworth, Nic, Allen, Kate   +3 more
core  

Resource guide for guidance counselors and teachers of students with sensory integration disorder and behavior attention problems [PDF]

, 2003
Plan BThe purpose of this resource guide was to develop sensory integration curriculum for guidance counselors and teachers who work with or have students with behavior or attention problems.
Peterson, Lauri Jo
core  

Correction to: Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human

Stem Cell Research & Therapy, 2021
Ryota Chijimatsu, Satoshi Miwa, Gensuke Okamura, Junya Miyahara, Naohiro Tachibana, Hisatoshi Ishikura, Junya Higuchi, Yuji Maenohara, Shinsaku Tsuji, Shin Sameshima, Kentaro Takagi, Keiu Nakazato, Kohei Kawaguchi, Ryota Yamagami, Hiroshi Inui, Shuji Taketomi, Sakae Tanaka, Taku Saito   +17 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Emergence of functional sensory subtypes as defined by transient receptor potential channel expression

, 2007
The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
Hjerling-Leffler, J, Ernfors, P, Ernfors, P,, Koltzenburg, M, AlQatari, M   +4 more
core   +1 more source

Novel nanobody-based tools for studying the synaptic vesicle life cycle [PDF]

BIO Web of Conferences
Rehm Ronja, Mougios Nikolaos, Real Karine Queiroz Zetune Villa, Sograte-Idrissi Shama, Albert László, Rahimi Amir M., Maidorn Manuel, Hentze Jannik, Martinez-Carranza Markel, Hosseini Hassan, Saal Kim-Ann, Oleksiievets Nazar, Prigge Matthias, Tsukanov Roman, Stenmark Pål, Rizzoli Silvio, Opazo Felipe, Fornasiero Eugenio   +17 more
doaj   +1 more source