Results 261 to 270 of about 1,385,596 (346)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Integrating Cutting-Edge Technologies in Food Sensory and Consumer Science: Applications and Future Directions. [PDF]

Foods
Lee D, Jeon H, Kim Y, Lee Y.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Longitudinal changes in sensory impairments and subsequent falls and fall-related injuries among middle-aged and older adults: a pooled analysis of four prospective cohorts. [PDF]

BMC Public Health
Nie J, Liao B, Wang X, Ferrari G, Rezende LFM, Qiu Y, Tao H, Le R.   +7 more
europepmc   +1 more source

Studies on Sensory Attributes of Kulfi Blended with Coconut (Cocos nucifera L.) Kernel Extract and Enriched with Whey Protein Powder

S.H. Terde, V.S. Dandekar, V. N. Patil, A. J. Mayekar, MC Kasture, KV Malshe, N. N. Prasade, Swapnil M. Bagul   +7 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Comparison of Analgesic Efficacy of Hyperbaric Levobupivacaine With or Without Clonidine in Patients Undergoing Intramedullary Nailing for Fracture Femur Under Subarachnoid Block: A Randomised Controlled Trial. [PDF]

Cureus
Chandra S, Rani P, Rautela RS, Salhotra R.   +3 more
europepmc   +1 more source

Research and Design Sensory Richness

Jin Tae Kim
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Physicochemical, sensory analysis and gastronomic significance of Sambal Tumpang as a traditional Javanese fermented condiment

Dyah Ari Wulandari, Anto Budiharjo, R. Haryo Bimo Setiarto, Severus Ryan Wisastra, Jose Abi Shalom Harris Purnama, Helga Zefanya Wical   +5 more
openalex   +1 more source