Results 51 to 60 of about 1,103,473 (317)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
, 2020 Sensory maps depict the world as it is qualitatively experienced, drawing on alternative human sensory modalities to call attention to the more-than-visual sensory characteristics of place. Sensory maps combine aesthetics with empirically sensed datasets
McLean, K.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
VARIABILITY IN SENSORY ECOLOGY: EXPANDING THE BRIDGE BETWEEN PHYSIOLOGY AND EVOLUTIONARY BIOLOGY
, 2009 International audienceSensory organs represent the interface between the central nervous system of organisms and the environment in which they live.
Irschick, Duncan +11 more
core +1 more source
Nature Communications, 2018 The sperm-specific solute carrier SLC9C1 is a phylogenetic chimaera that carries a voltage-sensing (VSD) and a cyclic nucleotide-binding domain (CNBD). Here authors show by electrophysiology and fluorimetry that SLC9C1 is a genuine Na+/H+ exchanger gated
F. Windler +6 more
doaj +1 more source
Frontiers in Integrative Neuroscience, 2009 A high incidence of sensory processing difficulties exists in children with Autism Spectrum Disorder (ASD) and children with idiopathic Sensory Modulation Disorder (SMD). This is the first study to directly compare and contrast these clinical disorders.
Sarah A Schoen +8 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Sodium channel inactivation kinetics of rat sensory and motor nerve fibres and their modulation by glutathione [PDF]
, 1993 Na+ channel currents of rat motor and sensory nerve fibres were studied with the patch-clamp technique on enzymatically demyelinated axons. Differences between motor and sensory fibres in multi-channel inactivation kinetics and the gating of late single ...
Quasthoff, Stefan +2 more
core +1 more source
OWSum: algorithmic odor prediction and insight into structure-odor relationships
Journal of Cheminformatics, 2023 We derived and implemented a linear classification algorithm for the prediction of a molecule’s odor, called Olfactory Weighted Sum (OWSum). Our approach relies solely on structural patterns of the molecules as features for algorithmic treatment and uses
Doris Schicker +3 more
doaj +1 more source