Results 71 to 80 of about 2,538,180 (361)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A study on vestibular-evoked myogenic potentials via galvanic vestibular stimulation in normal people

open access: yesJournal of Otology, 2018
Objectives: The aim of our study is to examine vestibular-evoked myogenic potentials (VEMPs) elicited by the galvanic vestibular stimulation in the sternocleidomastoid muscle (SCM) in healthy subjects for clinical applications of auditory neuropathy or ...
Ying Cheng, Yusuke Kimura, Kimitaka Kaga
doaj   +1 more source

Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors

open access: yesNature Communications, 2020
The role of gastrin related peptide (GRP+) neurons in itch is debated. Here, the authors generate a conditional knock-in mouse to label and manipulate GRP expressing DRG neurons and investigate their role in itch and nociception.
Devin M. Barry   +11 more
doaj   +1 more source

Identifying key environmental barriers experienced by persons with mild, moderate, or severe disability in Bankim Health District, Cameroon: a policy-targeted secondary analysis of data obtained with the World Bank and WHO model disability survey

open access: yesArchives of Public Health, 2021
Background Comprehensive data is key for evidence-informed policy aiming to improve the lives of persons experiencing different levels of disability.
Lindsay Lee   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Demographic and environmental factors associated with disability in India, Laos, and Tajikistan: a population-based cross-sectional study

open access: yesBMC Public Health, 2022
Background The number of people experiencing functional limitations due to health conditions (capacity) is expected to increase in low and middle-income countries as populations age and rates of non-communicable disease rise.
Michael Zhu Chen   +4 more
doaj   +1 more source

Simulation on sensory impairment in older adults:nursing education [PDF]

open access: yes, 2017
Sensory impairments are identified as the most common chronic and disabling conditions of later life impacting significantly on the quality of life and safety of older adults.
Croy, Suzanne   +2 more
core   +1 more source

Artificial Sensory Memory

open access: yesAdvances in Materials, 2019
Sensory memory, formed at the beginning while perceiving and interacting with the environment, is considered a primary source of intelligence. Transferring such biological concepts into electronic implementation aims at achieving perceptual intelligence,
Changjin Wan   +5 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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