Results 71 to 80 of about 42,218 (295)

Distal sensory polyneuropathy in HIV/TB co-infection : the role of vitamin B6 and N-acetyltransferase 2 genetic variation

, 2012
Both human immunodeficiency virus (HIV) infection and tuberculosis (TB) are complicated by a painful distal sensory polyneuropathy (DSP) that may be due to virus-related HIV-DSP, antiretroviral toxic neuropathy (ATN) or isoniazid-induced peripheral ...
Centner, Chad
core  

The Burden of Managing Medicines for Older People With Sensory Impairment: An Ethnographic-Informed Study

Gerontology and Geriatric Medicine
Background: Older age is associated with increased prevalence of sensory impairment and use of medicines. Objectives: To explore the daily “medicine journey” of older people with sensory impairment.
Peter Fuzesi PhD, Kirsten Broadfoot PhD, Marilyn Lennon PhD, Sabrina Anne Jacob PhD, Leah Macaden PhD, Annetta Smith PhD, Tomas Welsh PhD, Margaret C. Watson PhD   +7 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The role of audio visual aids in teaching English

, 2022
The present study aims at showing the role of audio-visual aids used in teaching English as well as investigating the effect of audio- visual aids in teaching English.
Waad, Mohanad Abdulkareem, Younus, Rand Zuhair   +1 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effect of processing aids on the quality of microwave foam-dried locust honey

Shipin yu jixie
ObjectiveTo investigate the effect of various processing aids on the quality of locust honey dried by microwave-assisted foam drying technology.MethodsSix processing aids, including egg white powder, soy protein isolate, maltodextrin, β-cyclodextrin ...
HAO Bingting, WANG Yingqiang, SHI Xixiong, ZHAO Hongxia   +3 more
doaj   +1 more source

Sensory Aids for the Blind Using Acoustics [PDF]

The Journal of the Acoustical Society of America, 1974
Blind people long have used acoustic cues and echoes, plus oral descriptions or reading, Talking Books, or recordings. To supplement a long cane or dog, an experimental ultrasonic sensor warns of objects at chest height. Binaural ultrasonic “spectacles” sense the environment and aid mobility.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hearing and vision rehabilitation for people with dementia in five European countries (SENSE-Cog): a randomised controlled trial

The Lancet. Healthy Longevity
Summary: Background: The effect of hearing and vision difficulties on the risk of developing dementia and worsening outcomes in people already living with dementia is well established.
Iracema Leroi, MD, ProfPhD Christopher J Armitage, MD, Elizabeth M Camacho, PhD, Anna Pavlina Charalambous, PhD, J P Connelly, MSc, ProfPhD Fofi Constantinidou, MSc, Renaud David, PhD, ProfPhD Piers Dawes, PhD, ProfPhD Rachel A Elliott, PhD, Mark Hann, PhD, Alison Holden, MSc, Emma Hooper, MSc, Sean P Kennelly, PhD, Evangelia Kontogianni, MSc, ProfMD Brian A Lawlor, MSc, Julie Longobardi, MSc, Luke Paterson, MSc, Antonis M Politis, PhD, ProfPhD David Reeves, PhD, Christine Schwimmer, PhD, Chryssoula Thodi, PhD, Mark Worthington, MSc, Wai Kent Yeung, PhD, Eric Frison, PhD   +23 more
doaj   +1 more source