Results 101 to 110 of about 5,916,094 (333)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Prevalence and clinical implications of nerve injury during bone patellar tendon bone harvesting for anterior cruciate ligament reconstruction

Journal of Orthopaedic Surgery, 2017
Purpose: Tendon harvesting for anterior cruciate ligament (ACL) reconstruction often injure sensory branches of the saphenous nerve (SN). Our purpose was to estimate the prevalence and postoperative course of sensory nerve injuries in bone patellar ...
Barak Haviv, Mustafa Yassin, Ehud Rath, Shlomo Bronak   +3 more
doaj   +1 more source

Ebi/AP-1 suppresses pro-apoptotic genes expression and permits long-term survival of Drosophila sensory neurons. [PDF]

PLoS ONE, 2012
Sensory organs are constantly exposed to physical and chemical stresses that collectively threaten the survival of sensory neurons. Failure to protect stressed neurons leads to age-related loss of neurons and sensory dysfunction in organs in which the ...
Young-Mi Lim, Shigeo Hayashi, Leo Tsuda
doaj   +1 more source

Sensory Changes in Adults with Unilateral Transtibial Amputation [PDF]

, 1998
The purpose of this study was to describe the sensory changes in adults with unilateral transtibial amputation (TTA), as any loss of sensation may have significant impact on the successful use of a prosthesis.
Kosasih, Judith B., Silver-Thorn, Barbara   +1 more
core   +1 more source

American Geriatrics Society and National Institute on Aging Bench-to-Bedside conference: sensory impairment and cognitive decline in older adults [PDF]

, 2018
This article summarizes the presentations and recommendations of the tenth annual American Geriatrics Society and National Institute on Aging Bench‐to‐Bedside research conference, “Sensory Impairment and Cognitive Decline,” on October 2–3, 2017, in ...
Cronin-Golomb, Alice, Cruickshanks, Karen J., Gilmore, Grover C., Lin, Frank R., Owsley, Cynthia, Peelle, Jonathan E., Recanzone, Gregg, Sharma, Anu, Swenor, Bonnielin, Whitson, Heather E., Yaffe, Kristine   +10 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Associations between subjective and objective measures of stress and load: an insight from 45-week prospective study in 189 elite athletes

Frontiers in Psychology
IntroductionThe aim of this study was to investigate the associations between subjective and objective measures of stress and load in elite male handball players at both the group and individual levels.MethodsIn this 45-week prospective cohort study, 189
Kristina Drole, Mojca Doupona, Kathrin Steffen, Kathrin Steffen, Aleš Jerin, Aleš Jerin, Armin Paravlic, Armin Paravlic   +7 more
doaj   +1 more source

The benefits of sensation on the experience of a hand: A qualitative case series.

PLoS ONE, 2019
BackgroundThe experience of upper limb loss involves loss of both functional capabilities and the sensory connection of a hand. Research studies to restore sensation to persons with upper limb loss with neural interfaces typically measure outcomes ...
Emily L Graczyk, Anisha Gill, Dustin J Tyler, Linda J Resnik   +3 more
doaj   +1 more source

A scoping review of the pharmaceutical care needs of people with sensory loss

International Journal of Pharmacy Practice, 2018
This scoping review collated evidence of the pharmaceutical care needs of people with sensory loss (SL).
K. Killick, Leah Macaden, Annetta Smith, T. Kroll, Kathleen M Stoddart, M. Watson   +5 more
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source