Results 131 to 140 of about 5,916,094 (333)

Audiovisual Temporal Perception in Aging: The Role of Multisensory Integration and Age-Related Sensory Loss

open access: yesFrontiers in Human Neuroscience, 2018
Within each sensory modality, age-related deficits in temporal perception contribute to the difficulties older adults experience when performing everyday tasks.
Cassandra J. Brooks   +3 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Effect of Sensory Loss on Improvements of Upper-Limb Paralysis Through Robot-Assisted Training: A Preliminary Case Series Study

open access: yesApplied Sciences, 2019
Sensory disorder is a factor preventing recovery from motor paralysis after stroke. Although several robot-assisted exercises for the hemiplegic upper limb of stroke patients have been proposed, few studies have examined improvement in function in stroke
Hiroyuki Miyasaka   +4 more
doaj   +1 more source

A novel mutation in KIF5A in a Malian family with spastic paraplegia and sensory loss

open access: yesAnnals of Clinical and Translational Neurology, 2017
Hereditary spastic paraplegias (HSPs) are well‐characterized disorders but rarely reported in Africa. We evaluated a Malian family in which three individuals had HSP and distal muscle atrophy and sensory loss.
C. Guinto   +13 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Large-scale audiometric phenotyping identifies distinct genes and pathways involved in hearing loss subtypes

open access: yesCommunications Biology
Age-related hearing loss affects one-third of the population over 65 years. However, the diverse pathologies underlying these heterogeneous phenotypes complicate genetic studies. Here we show that by applying computational phenotyping approaches based on
Samah Ahmed   +6 more
doaj   +1 more source

Faktor-Faktor yang Berhubungan dengan Gangguan Pendengaran Tipe Sensorineural Tenaga Kerja Unit Produksi PT.Kurnia Jati Utama Semarang [PDF]

open access: yes, 2005
Background : PT. Kurnia Jati Utama is a wood processing company. Noise intensity in production room was passing over the threshold limit value (TLV) 85 dB (A). Workers work continuously over 8 hours a day or even more. If that noise exposure expose for 8
Arini, E. Y. (Evi)   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Adaptation to sensory loss : Adaptation to sensory loss

open access: yes, 2010
The human brain has the remarkable ability to adapt to changes in its environment by benefiting from its ‘plastic’ properties. Following brain injury, the amputation of a limb, or the loss of a sensory input such as peripheral blindness, brain circuitry often seems to be able to reorganize itself in order to compensate for the handicap by being ...
Voss, Patrice   +3 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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