Results 51 to 60 of about 388,750 (275)
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Acetylcholine Regulates Olfactory Perceptual Learning through Effects on Adult Neurogenesis
iScience, 2019 Summary: Learning to perceptually discriminate between chemical signals in the environment (olfactory perceptual learning [OPL]) is critical for survival.
Arielle Schilit Nitenson +6 more
doaj +1 more source
iScience, 2023 Summary: The COVID-19 pandemic brought attention to our limited understanding of human olfactory physiology. While the cellular composition of the human olfactory epithelium is similar to that of other vertebrates, its functional properties are largely ...
Andres Hernandez-Clavijo +11 more
doaj +1 more source
Weak universality in sensory tradeoffs [PDF]
, 2016 For many organisms, the number of sensory neurons is largely determined during development, before strong environmental cues are present. This is despite the fact that environments can fluctuate drastically both from generation to generation and within ...
DeDeo, Simon, Marzen, Sarah
core +2 more sources
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
The Backside of Habit: Notes on Embodied Agency and the Functional Opacity of the Medium [PDF]
, 2020 In this chapter what I call the “backside” of habit is explored. I am interested in the philosophical implications of the physical and physiological processes that mediate, and which allow for what comes to appear as almost magic; namely the various ...
Brincker, Maria
core
An interoceptive predictive coding model of conscious presence [PDF]
, 2012 We describe a theoretical model of the neurocognitive mechanisms underlying conscious presence and its disturbances. The model is based on interoceptive prediction error and is informed by predictive models of agency, general models of hierarchical ...
Anil K. Seth +5 more
core +3 more sources
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source
BiomoleculesUsher syndrome, a rare genetic disorder causing both hearing and vision loss, presents significant diagnostic and therapeutic challenges due to its complex genetic basis.
Rama Krishna Thelagathoti +6 more
doaj +1 more source
TMS-induced Neural Noise in Sensory Cortex Interferes with Short-term Memory Storage in Prefrontal Cortex [PDF]
, 2014 In a previous study, Harris et al. (2002) found disruption of vibrotactile short-term memory after applying single-pulse transcranial magnetic stimulation (TMS) to primary somatosensory cortex (SI) early in the maintenance period, and suggested that this
Bancroft, Tyler D. +3 more
core +2 more sources