Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Cardiac Remote Conditioning and Clinical Relevance: All Together Now!
Acute myocardial infarction (AMI) is the leading cause of death and disability worldwide. Timely reperfusion is the standard of care and results in decreased infarct size, improving patient survival and prognosis.
Kristin Luther +4 more
doaj +1 more source
Robust conditioned flavor preferences with a sensory preconditioning procedure [PDF]
During sensory preconditioning, rats were given two distinct flavors (saccharin and coffee) in sequence with 0, 9, or 27 sec between the two flavors. A control group received the flavors unpaired. In subsequent training, the second flavor preceded sucrose by 5 min.
E A, Lyn, E D, Capaldi
openaire +2 more sources
Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones [PDF]
AIMS: Innate mechanisms of inter-organ protection underlie the phenomenon of remote ischaemic preconditioning (RPc) in which episode(s) of ischaemia and reperfusion in tissues remote from the heart reduce myocardial ischaemia/reperfusion injury.
Ackland, GL +9 more
core +1 more source
A multilayered small‐caliber vascular scaffold combining electrospinning and 4‐axis printing is developed and biofunctionalized with marine sulfated polysaccharides from Holothuria tubulosa. The resulting construct exhibits enhanced hemocompatibility, tunable mechanical properties, and supports endothelial and smooth muscle cell adhesion and ...
Gabriele Obino +9 more
wiley +1 more source
Identifying the Source of a Humoral Factor of Remote (Pre)Conditioning Cardioprotection.
Signalling pathways underlying the phenomenon of remote ischaemic preconditioning (RPc) cardioprotection are not completely understood. The existing evidence agrees that intact sensory innervation of the remote tissue/organ is required for the release ...
Svetlana Mastitskaya +5 more
doaj +1 more source
High‐Throughput In Vivo Subcellular Analysis of Gold Nanoparticles for Tumor Mitochondrial Targeting
A DNA barcoding system enables high‐throughput in vivo screening of mitochondrial‐targeting gold nanoparticles. Thirty nanoparticle types with varied shapes, sizes, and ligands are individually barcoded and pooled. The pooled library is administered to tumor‐bearing mice, and barcodes retrieved from tumor mitochondria are amplified and sequenced to ...
Xingyue Huang +8 more
wiley +1 more source
PVC-Based Cerium Phosphate Membrane Exhibiting Selectivity for Molybdate Anions [PDF]
A PVC-based membrane containing cerium phosphate was developed. Unlike the cerium phosphate itself that acts as a cation exchanger, the membrane exhibited anion-exchange properties.
Hassan Khodakarami +1 more
doaj
Intrinsic cardiac ganglia and acetylcholine are important in the mechanism of ischaemic preconditioning [PDF]
This study aimed to investigate the role of the intrinsic cardiac nervous system in the mechanism of classical myocardial ischaemic preconditioning (IPC).
Burke, N +3 more
core +1 more source
Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes
Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar +7 more
wiley +1 more source

