Results 71 to 80 of about 11,638 (270)

Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury

open access: yesNeurobiology of Disease, 2015
Nerve injury can lead to axonal regeneration, axonal degeneration, and/or neuronal cell death. Remarkably, the MAP3K dual leucine zipper kinase, DLK, promotes each of these responses, suggesting that DLK is a sensor of axon injury.
Vera Valakh   +4 more
doaj   +1 more source

Rapid Isolation of Dorsal Root Ganglion Macrophages. [PDF]

open access: yes, 2019
There are growing interests to study the molecular and cellular interactions among immune cells and sensory neurons in the dorsal root ganglia after peripheral nerve injury.
Guan, Zhonghui   +2 more
core  

Poking Pluripotency: Nanoinjection Into Human iPSCs

open access: yesAdvanced Materials, EarlyView.
Nanoinjection into hiPSCs: silicon nanotubes effectively transfect human induced pluripotent stem cells (hiPSCs) with mRNA, enabled by a delayed extracellular matrix application and enhanced surface functionalization. Nanoinjection is demonstrated with several reporter mRNA, including co‐transfection of mCherry and GFP.
Jann Harberts   +5 more
wiley   +1 more source

Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization

open access: yesJournal of Neuroinflammation, 2020
Background Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano-sized exosomes have shown great potential for promoting functional ...
Wei Liu   +14 more
doaj   +1 more source

Powder‐to‐Film Conversion of Nickel Single‐Atom Catalysts into Binder‐Free and Resistant Electrodes

open access: yesAdvanced Materials Interfaces, EarlyView.
A reproducible strategy is reported for fabricating standalone thin‐film electrodes composed of CNx‐supported Ni single‐atom catalysts. The resulting binder‐free electrodes exhibit robust stability, enhanced charge transfer, and superior electrochemical performance, offering scalable opportunities for applications in electrochemistry. ABSTRACT Although
Milla Vigliengo   +8 more
wiley   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Damage to Posterior Parietal Cortex Impairs Two Forms of Relational Learning

open access: yesFrontiers in Integrative Neuroscience, 2012
The posterior parietal cortex (PPC) is a component of a major corticohippocampal circuit that is involved in relational learning, yet the specific contribution of PPC to hippocampal-dependent learning is unresolved.
Siobhan eRobinson, David John Bucci
doaj   +1 more source

Intrathecal morphine remotely preconditions the heart via a neural pathway [PDF]

open access: yes, 2012
Central opioid receptor activation triggers cardioprotection against ischemia reperfusion injury, independent of peripheral opioid receptor activity. Using a rodent model of myocardial ischemia reperfusion injury with infarct size as the primary outcome,
Irwin, MG, Wong, GTC, Xia, Z, Yao, L
core   +1 more source

Grounding Large Language Models for Robot Task Planning Using Closed‐Loop State Feedback

open access: yesAdvanced Robotics Research, EarlyView.
BrainBody‐Large Language Model (LLM) introduces a hierarchical, feedback‐driven planning framework where two LLMs coordinate high‐level reasoning and low‐level control for robotic tasks. By grounding decisions in real‐time state feedback, it reduces hallucinations and improves task reliability.
Vineet Bhat   +4 more
wiley   +1 more source

Preventing the development of observationally learnt fears in children by devaluing the model's negative response [PDF]

open access: yes, 2015
Vicarious learning has become an established indirect pathway to fear acquisition. It is generally accepted that associative learning processes underlie vicarious learning; however, whether this association is a form of conditioned stimulus-unconditioned
Askew, Chris   +2 more
core   +1 more source

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