Results 81 to 90 of about 11,638 (270)

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

The Potential of Stem Cell Therapy to Repair White Matter Injury in Preterm Infants: Lessons Learned From Experimental Models

Frontiers in Physiology, 2019
Diffuse white matter injury (dWMI) is a major cause of morbidity in the extremely preterm born infant leading to life-long neurological impairments, including deficits in cognitive, motor, sensory, psychological, and behavioral functioning.
Josine E. G. Vaes, Josine E. G. Vaes, Marit A. Vink, Caroline G. M. de Theije, Freek E. Hoebeek, Manon J. N. L. Benders, Cora H. A. Nijboer   +6 more
doaj   +1 more source

Regulation of Microtubule Dynamics in Axon Regeneration: Insights from C. elegans. [PDF]

, 2016
The capacity of an axon to regenerate is regulated by its external environment and by cell-intrinsic factors. Studies in a variety of organisms suggest that alterations in axonal microtubule (MT) dynamics have potent effects on axon regeneration.
CHISHOLM, Andrew, Tang, Ngang
core   +2 more sources

Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System

Advanced Science, EarlyView.
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu, Bowen Zhu, Shicheng Zhang, Keren Li, Xianchen Wu, Yazhi Pi, Jie Yan, Daigao Chen, Bingli Guo, Xi Xiao, Lei Wang, Xiaochuan Xu, Xuwei Xue, Shanguo Huang, Zizheng Cao, Shaohua Yu   +15 more
wiley   +1 more source

Rats distinguish between absence of events and lack of evidence in contingency learning. [PDF]

, 2012
The goal of three experiments was to study whether rats are aware of the difference between absence of events and lack of evidence. We used a Pavlovian extinction paradigm in which lights consistently signaling sucrose were suddenly paired with the ...
Aaron P. Blaisdell, AP Blaisdell, AP Blaisdell, AP Blaisdell, AR Delamater, AR Delamater, BL Thomas, CD Fast, IP Pavlov, Jared Wong, JM Pearce, KJ Leising, Martina Schmid, ME Bouton, ME Bouton, Michael R. Waldmann, MJW Larkin, MR Papini, P Holland, RA Rescorla, RM Colwill   +20 more
core   +2 more sources

Improving the Skin‐Conformability of Wearable Continuous Glucose Monitors With Synthetic Hydrogel Electrodes

Advanced Science, EarlyView.
A synthetic hydrogel electrode for skin‐conformable enzymatic biosensing is presented, featuring a stretchable, tape‐shaped continuous glucose monitor for non‐invasive diabetes management. ABSTRACT Synthetic bioelectronics is rapidly advancing, propelled by breakthroughs in synthetic biology and bioelectronics.
Binbin Cui, Shilei Dai, Ivo Pang, Dingyao Liu, Xinran Zhang, Jing Bai, Xinyu Tian, Shiming Zhang   +7 more
wiley   +1 more source

Involvement of neuronal pathways in the protective effects of hindlimb perconditioning during renal ischemia [PDF]

, 2017
Remote ischemic perconditioning (RPEC) is a therapeutic intervention that has been demonstrated to reduce renal ischemia/reperfusion (I/R) injury. However, the underlying renal protective mechanism remains unclear.
AHGHARI, PARISA, AKBARI, ZAHRA, KADKHODAEE, MEHRI, POURKHALILI, KHALIL, SADEGHI, MEHDI, SEDAGHAT, ZAHRA, SEIFI, BEHJAT   +6 more
core   +3 more sources

Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A‐Dependent hnRNPA2B1/COX‐2 Axis

Advanced Science, EarlyView.
Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li, Zehao Guo, Yutong Zou, Jiongfeng Zhang, Jixiang Shi, Xihong Fu, Jian Tu, Hao Yao, Xuanxuan Lu, Lili Wen, Xianbiao Xie   +10 more
wiley   +1 more source

Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury [PDF]

, 2008
Copyright: © 2008 Song et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Li, Fang, Zhang, Feng-He, Zhong, Jin Hua, Zhou, Xin-Fu, Song, Xingyun   +4 more
core   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source