Results 91 to 100 of about 766,171 (351)

Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation

open access: yeseLife, 2015
Analysis of brain ultrastructure using electron microscopy typically relies on chemical fixation. However, this is known to cause significant tissue distortion including a reduction in the extracellular space.
Natalya Korogod   +2 more
doaj   +1 more source

Sensory processing and world modeling for an active ranging device [PDF]

open access: yes
In this project, we studied world modeling and sensory processing for laser range data. World Model data representation and operation were defined.
Hong, Tsai-Hong, Wu, Angela Y.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Evaluation and salivary biochemistry associations of sour-salty taste interaction

open access: yesJournal of Future Foods
: Taste interaction is a well-known phenomenon in sensory studies, but how to quantify the magnitude of the effect of one tastant on other taste attribute(s) is still largely unsolved, let alone further explorations from a salivary biochemistry ...
Hongnan Jiang   +4 more
doaj   +1 more source

Effect of pressing method on the sensory quality of organic apple juice [PDF]

open access: yes, 2016
There is a need for alternative, gentle processing methods that can be used for processing of organic food products. The pressing methods used for organic apple juice include the slow rack-and-frame press and the faster water press or belt press. The aim
Eggers, Nina   +3 more
core  

Simulating Cortical Feedback Modulation as Changes in Excitation and Inhibition in a Cortical Circuit Model. [PDF]

open access: yes, 2016
Cortical feedback pathways are hypothesized to distribute context-dependent signals during flexible behavior. Recent experimental work has attempted to understand the mechanisms by which cortical feedback inputs modulate their target regions.
McCormick, David A   +2 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Modularity and the predictive mind [PDF]

open access: yes, 2017
Modular approaches to the architecture of the mind claim that some mental mechanisms, such as sensory input processes, operate in special-purpose subsystems that are functionally independent from the rest of the mind.
Drayson, Zoe
core   +1 more source

Visual Spike-based Convolution Processing with a Cellular Automata Architecture [PDF]

open access: yes, 2010
this paper presents a first approach for implementations which fuse the Address-Event-Representation (AER) processing with the Cellular Automata using FPGA and AER-tools.
Cerdá, J.   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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