Results 251 to 260 of about 173,264 (311)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Nicotinic acetylcholine receptors in pain modulation. [PDF]

Front Pharmacol
Cheng J, Chang J, Li S.
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A neuroimmune axis linking S100A8/9 to itch sensitization in both bullous pemphigoid and atopic dermatitis. [PDF]

JID Innov
Lawson K, Nho Y, Stewart R, Wu S, Cole EF, Herrera D, Chisolm S, Feldman R, Han L.   +8 more
europepmc   +1 more source

REGENERATION OF VERTEBRATE SENSORY RECEPTOR-CELLS - FINAL GENERAL DISCUSSION

, 1991
RUBEL, EW, WATT, FM, POTTEN, CS, FARBMAN, AI, LEWIS, J, CALOF, AL, MARGOLIS, FL, REH, JA, RAYMOND, PA, CORWIN, JT, PRESSON, JC, FERNALD, RD, STEINBERG, RH, COTANCHE, DA, REASNER, DA, OAKLEY, B, RYALS, BM   +16 more
openaire   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

The Role of Neuritin 1 in Synaptic Plasticity and Sensory Nerve Function: Integrator of Neurotrophic, Metabolic and Injury Signals. [PDF]

Eur J Neurosci
Agrawal J, Escola MV, Jones SW, Chapman V, Dajas-Bailador F.   +4 more
europepmc   +1 more source

Somatosensory Functions of Melastatin Transient-Receptor Potential Channels in the Teeth: Molecular Basis for Thermal Dentine Hypersensitivity. [PDF]

Dent J (Basel)
Méndez R, Martín-Cruces J, Anache M, Teulé-Trull M, García-Mesa Y, Cuendias P, Vega JA, Cobo T.   +7 more
europepmc   +1 more source

NLRP3 and RANK-RANKL-OPG Pathway-related Gene Expression Levels in Children With Autism Spectrum Disorder. [PDF]

In Vivo
Kara B, Savaş M, Özer T, Şişmanlar ŞG, Akarsu R, Öztürk SY, Akpinar ŞN, Deniz A, Güneş AS, Dursun F, Akkoyunlu DS, Çine N, Tüzün E.   +12 more
europepmc   +1 more source