Results 11 to 20 of about 526,955 (247)

Transplanting Neural Progenitor Cells into a Chronic Dorsal Column Lesion Model

Biomedicines, 2022
Cell transplantation therapy is a promising strategy for spinal cord injury (SCI) repair. Despite advancements in the development of therapeutic strategies in acute and subacute SCI, much less is known about effective strategies for chronic SCI.
Kazuo Hayakawa, Ying Jin, Julien Bouyer, Theresa M. Connors, Takanobu Otsuka, Itzhak Fischer   +5 more
doaj   +1 more source

Associations of clinical outcomes and MRI findings in intra-articular administration of autologous adipose-derived stem cells for knee osteoarthritis

Regenerative Therapy, 2020
Introduction: Clinical studies of intra-articular injection of mesenchymal stem cells for osteoarthritis (OA) indicate its efficacy. Here, we retrospectively investigated the associations of pretherapeutic magnetic resonance imaging (MRI) findings with ...
Junya Higuchi, Ryota Yamagami, Takumi Matsumoto, Tomohiro Terao, Keita Inoue, Shinsaku Tsuji, Yuji Maenohara, Tokio Matsuzaki, Ryota Chijimatsu, Yasunori Omata, Fumiko Yano, Sakae Tanaka, Taku Saito   +12 more
doaj   +1 more source

The superficial zone of articular cartilage

Inflammation and Regeneration, 2022
The superficial zone of articular cartilage contributes to smooth joint motion through the production of proteoglycan 4 (PRG4), also known as lubricin.
Taku Saito
doaj   +1 more source

Nondeterministic nature of sensorineural outcomes following noise trauma

Biology Open, 2021
Over 1.1 billion individuals are at risk for noise induced hearing loss yet there is no accepted therapy. A long history of research has demonstrated that excessive noise exposure will kill outer hair cells (OHCs).
O'neil W. Guthrie, Ishan S. Bhatt
doaj   +1 more source

Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes

Nature Communications, 2016
Rela is a transcription factor shown to have seemingly contradictory roles in anabolism and catabolism of cartilage. Here the authors find that Rela prevents chondrocyte apoptosis and that homozygous knockout causes accelerated osteoarthritis in adults ...
Hiroshi Kobayashi, Song Ho Chang, Daisuke Mori, Shozo Itoh, Makoto Hirata, Yoko Hosaka, Yuki Taniguchi, Keita Okada, Yoshifumi Mori, Fumiko Yano, Ung-il Chung, Haruhiko Akiyama, Hiroshi Kawaguchi, Sakae Tanaka, Taku Saito   +14 more
doaj   +1 more source

3D Indoor Positioning of UAVs with Spread Spectrum Ultrasound and Time-of-Flight Cameras

Sensors, 2017
This work proposes the use of a hybrid acoustic and optical indoor positioning system for the accurate 3D positioning of Unmanned Aerial Vehicles (UAVs). The acoustic module of this system is based on a Time-Code Division Multiple Access (T-CDMA) scheme,
José A. Paredes, Fernando J. Álvarez, Teodoro Aguilera, José M. Villadangos   +3 more
doaj   +1 more source

Midterm results of revision total hip arthroplasty for migrated bipolar hemiarthroplasty in patients with hip osteoarthritis using cementless cup with the rim-fit technique

Journal of Orthopaedic Surgery, 2020
Purpose: The results of reamed bipolar hemiarthroplasty (BHA) in patients with hip osteoarthritis (OA) are reported to be unfavorable. Acetabular reaming for sufficient bony coverage caused bipolar head migration into the superomedial direction, and most
Takeyuki Tanaka, Taizo Kaneko, Ryo Hidaka, Kazuaki Hashikura, Hisatoshi Ishikura, Toru Moro, Sakae Tanaka   +6 more
doaj   +1 more source

Calculation of the Coupling Coefficient in Step-Index Multimode Polymer Optical Fibers Based on the Far-Field Measurements

Frontiers in Physics, 2022
Using the power flow equation (PFE), this article investigates mode coupling in step-index (SI) multimode (MM) polymer optical fiber (POF). This equation’s coupling coefficient was initially fine-tuned so that it could appropriately reconstruct ...
Svetislav Savović, Svetislav Savović, Alexandar Djordjevich, Branko Drljača, Ana Simović, Rui Min   +5 more
doaj   +1 more source

Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone

Arthritis Research & Therapy, 2019
Background Both loss- and gain-of-function of Wnt/β-catenin signaling in chondrocytes result in exacerbation of osteoarthritis (OA). Here, we examined the activity and roles of Wnt/β-catenin signaling in the superficial zone (SFZ) of articular cartilage.
Fengjun Xuan, Fumiko Yano, Daisuke Mori, Ryota Chijimatsu, Yuji Maenohara, Hideki Nakamoto, Yoshifumi Mori, Yuma Makii, Takeshi Oichi, Makoto Mark Taketo, Hironori Hojo, Shinsuke Ohba, Ung-il Chung, Sakae Tanaka, Taku Saito   +14 more
doaj   +1 more source

Walking-Related Dual-Task Interference in Early-to-Middle-Stage Huntington's Disease: An Auditory Event Related Potential Study

Frontiers in Psychology, 2017
Objective: To compare interference between walking and a simple P3 auditory odd-ball paradigm in patients with Huntington's disease (HD) and age- and sex-matched controls.Methods: Twenty-four early-to-middle-stage HD patients and 14 age- and sex-matched ...
Marina de Tommaso, Katia Ricci, Anna Montemurno, Eleonora Vecchio, Sara Invitto   +4 more
doaj   +1 more source