Results 21 to 30 of about 526,955 (247)

Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway

open access: yesNature Communications, 2019
Excessive mechanical stress promotes the development of osteoarthritis. Here Chang et al. identify gremlin-1 as a factor expressed in chondrocytes in response to mechanical stress, and contributing to osteoarthritis via activation of the NF-κB pathway.
Song Ho Chang   +16 more
doaj   +1 more source

Roboethics in Remote Human Interactions and Rehabilitative Therapeutics

open access: yesApplied Sciences, 2022
Global aging, the need for continuous high-quality services, and the recent COVID-19 pandemic have caused many sectors to reduce in-person contact between individuals where possible, and to instead use remote communication technology.
Ali Maddahi   +6 more
doaj   +1 more source

Heatwave-Like Events During Development Are Sufficient to Impair Bumblebee Worker Responses to Sensory Stimuli

open access: yesFrontiers in Ecology and Evolution, 2022
Heatwaves are increasingly common globally and are known to have detrimental impacts on animal morphology and behaviour. These impacts can be severe, especially if heatwaves occur during development, even on animals that can regulate the temperature of ...
Craig D. Perl   +10 more
doaj   +1 more source

Capsaicin-Induced Skin Desensitization Differentially Affects A-Delta and C-Fiber-Mediated Heat Sensitivity

open access: yesFrontiers in Pharmacology, 2020
Localized neuropathic pain can be relieved following the topical application of high-concentration capsaicin. This clinical effect is thought to be related to the temporary desensitization of capsaicin- and heat-sensitive epidermal nociceptors.
Sabien G. A. van Neerven, André Mouraux
doaj   +1 more source

Brain networking analysis in migraine with and without aura

open access: yesThe Journal of Headache and Pain, 2017
Background To apply effective connectivity by means of nonlinear Granger Causality (GC) and brain networking analysis to basal EEG and under visual stimulation by checkerboard gratings with 0.5 and 2.0 cpd as spatial frequency in migraine with aura (MA ...
Marina de Tommaso   +5 more
doaj   +1 more source

Laser Evoked Potentials in Early and Presymptomatic Huntington’s Disease

open access: yesBehavioural Neurology, 2016
Pain was rarely studied in Huntington’s disease (HD). We presently aimed to extend our previous study on pain pathways functions by laser evoked potentials (LEPs) to a larger cohort of early unmedicated HD patients and a small group of presymptomatic HD (
Marina de Tommaso   +4 more
doaj   +1 more source

Circadian rhythms of migraine attacks in episodic and chronic patients: a cross sectional study in a headache center population

open access: yesBMC Neurology, 2018
Background Migraine is considered a disease with diurnal and 24 h pattern, though the existence of a prevalent circadian rhythm associated to migraine frequency and severity is still not clear. This observational cross-sectional study aimed to: 1. Assess
Marina de Tommaso, Marianna Delussi
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine   +10 more
wiley   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

Useful parameters for the motion analysis of facial skin care in Japanese women

open access: yesJournal of Physiological Anthropology, 2020
Background Facial skin care (FSC) is an important routine for Japanese women. Hand motions during FSC physically affect psychological state. However, it is very difficult to evaluate hand motions during personal and complex FSC.
Shingo Sakai   +3 more
doaj   +1 more source

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