Results 61 to 70 of about 1,275,418 (346)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

How Listing's Law May Emerge from Neural Control of Reactive Saccades [PDF]

open access: yes, 1995
We hypothesize that Listing's Law emerges as a result of two key properties of the saccadic sensory-motor system: 1) The visual sensory apparatus has a 2-D topology and 2) motor synergists are synchronized.
Bullock, Daniel, Pribe, Christopher A.
core   +1 more source

Prepontine non-giant neurons drive flexible escape behavior in zebrafish [PDF]

open access: yes, 2019
Many species execute ballistic escape reactions to avoid imminent danger. Despite fast reaction times, responses are often highly regulated, reflecting a trade-off between costly motor actions and perceived threat level.
Bergeron, S.   +4 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Short-term overloading exercise attenuates articular chondrocyte features partly via synovium–cartilage interactions mediated by inhibin subunit beta A

open access: yesScientific Reports
Excessive mechanical loading leads to cartilage degeneration. However, short-term responses of the synovium and cartilage to overloading and interactions between these tissues remain poorly understood.
Yusuke Arino   +6 more
doaj   +1 more source

Useful parameters for the motion analysis of facial skin care in Japanese women

open access: yesJournal of Physiological Anthropology, 2020
Background Facial skin care (FSC) is an important routine for Japanese women. Hand motions during FSC physically affect psychological state. However, it is very difficult to evaluate hand motions during personal and complex FSC.
Shingo Sakai   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The development of scientific reasoning of preschool children: Micro-analysis of mind–material–body integration

open access: yesSouth African Journal of Childhood Education, 2019
Background: This article argues that the emergence of scientific reasoning in the preschool years could be augmented by caregivers and preschool teachers through nurturing ‘Habits of Mind’ (HOM) and ‘Habits of Body’ (HOB) of young children.
Retha van Niekerk
doaj   +1 more source

Laryngeal sensitivity in patients with amyotrophic lateral sclerosis [PDF]

open access: yes, 2016
Recent studies have shown the involvement of the sensory nervous system in patients with amyotrophic lateral sclerosis (ALS). The aim of our study was to investigate the correlation between the laryngeal sensitivity deficit and the type of ALS onset ...
BIASIOTTA, ANTONELLA   +13 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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