Results 161 to 170 of about 334,209 (303)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Review of sensory systems deployed by epidermal keratinocytes. [PDF]
Denda M, Elias PM.
europepmc +1 more source
Cambrian comb jellies from Utah illuminate the early evolution of nervous and sensory systems in ctenophores. [PDF]
Parry LA +3 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
How Single-Cell Transcriptomics of Hydractinia Is Informing the Evolution of Cnidarian Sensory Systems. [PDF]
Schnitzler CE, Song J, de Jong D.
europepmc +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Artificial Intelligence-Enabled Intelligent Sensory Systems for Quality Evaluation of Traditional Chinese Medicine: A Review of Electronic Nose, Electronic Tongue, and Machine Vision Approaches. [PDF]
Shi J, Wu J, Xu L, Tang C, Zhang Y.
europepmc +1 more source
Relative Contribution of Proprioceptive and Vestibular Sensory Systems to Locomotion: Opportunities for Discovery in the Age of Molecular Science. [PDF]
Akay T, Murray AJ.
europepmc +1 more source

