Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Nanomaterials for Sensory Systems-A Review. [PDF]
Ivanov A +4 more
europepmc +1 more source
The impact of premature extrauterine exposure on infants' stimulus-evoked brain activity across multiple sensory systems. [PDF]
Schmidt Mellado G +10 more
europepmc +1 more source
The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Robert Riener, Luca Vassella, Peter Wolf
doaj +1 more source
Evolution of sensory systems underlies the emergence of predatory feeding behaviors in nematodes. [PDF]
Roca M +6 more
europepmc +1 more source
Human hippocampal connectivity is stronger in olfaction than other sensory systems. [PDF]
Zhou G +9 more
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Examining Sensory Systems That Contribute to Falls in Parkinson Disease Using Computerized Dynamic Posturography: Secondary Analysis. [PDF]
Rivera M.
europepmc +1 more source
Anaesthetics and plants: from sensory systems to cognition-based adaptive behaviour. [PDF]
Baluška F, Yokawa K.
europepmc +1 more source

