Results 171 to 180 of about 334,209 (303)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant. [PDF]

G3 (Bethesda)
Dang NDP, Barcus AK, Conklin CL, Truong TQ, Vivian MD, Wang J, Thomas HR, Parant JM, Yeo NC, Thyme SB.   +9 more
europepmc   +1 more source

Attention related oscillatory activity within sensory systems

, 1997
Andrzej Wróbel
openalex   +1 more source

Effects of a Plant‐Based Diet During the First Month of Feeding on Alevin Rainbow Trout ( Oncorhynchus mykiss ) in the Development of Tongue Sensory System Regulating Feeding Behavior [PDF]

Maud Martinat, Amelle Varvarais, Cécile Heraud, Anne Surget, Anthony Lanuque, Frédéric Terrier, Jérôme Roy   +6 more
openalex   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

How Foraging Mode Sculpts Sensory Systems: Morphological Evidence From DiceCT and Histology in Sympatric Lizards. [PDF]

Ecol Evol
Leng L, Shi L.
europepmc   +1 more source

Contribution of crosslinking products in the flavour enhancer processing: the new concept of Maillard peptide in sensory characteristics of Maillard reaction systems [PDF]

, 2016
Eric Karangwa, Nicole Murekatete, Jean de Dieu Habimana, Kingsley Masamba, Emmanuel Duhoranimana, Bertrand Muhoza, Xiaoming Zhang   +6 more
openalex   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Bio-Inspired Neuromorphic Sensory Systems from Intelligent Perception to Nervetronics. [PDF]

Adv Sci (Weinh)
Boahen EK, Kweon H, Oh H, Kim JH, Lim H, Kim DH.   +5 more
europepmc   +1 more source