Results 41 to 50 of about 30,607 (232)

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Sentinel Node Biopsy in Young Patients with Atypical Melanocytic Tumors of the Head and Neck

OTO Open, 2019
Objective To examine the diagnostic value of the sentinel lymph node biopsy in pediatric through young adult head and neck melanocytic tumors of unknown malignant potential. Study Design Retrospective case series.
David Pfau, Akina Tamaki MD, Kathryn R. Hoppe MD, Kord Honda MD, Rod Rezaee MD, Chad A. Zender MD   +5 more
doaj   +1 more source

The Sentinel Lymph Node in Breast Cancer: Problems Posed by Examination During Surgery. A Review of Current Literature and Management

Frontiers in Surgery, 2018
The presence of tumor cells can be identified in the lymph node when metastasis has occurred from the primary cancer site into the lymph node (1) If the sentinel lymph node ganglion is negative for the presence of tumor cells at the time of histological ...
Jean Bouquet de Jolinière, A. Major, F. Khomsi, N. Ben Ali, L. Guillou, A. Feki   +5 more
doaj   +1 more source

The role of defining the sentinel lymph node in the treatment of low-risk highly differentiated thyroid cancer (review of literature)

Вестник хирургии имени И.И. Грекова, 2020
The definition of a sentinel lymph node is a technique that appeared at the middle of the 20th century. For a number of malignant neoplasms, the definition of a sentinel lymph node is standard procedure, but for highly differentiated thyroid cancer, the ...
M. E. Boriskova, U. V. Farafonova, P. A. Pankova, M. A. Bykov, E. A. Ramazanova, N. S. Feshenko, A. A. Zakharenko, N. A. Yaitsky   +7 more
doaj   +1 more source

The Squalene Oil‐in‐Water Nanoemulsion Vaccine Carrier AddaVax Potentiates TLR‐Induced B‐Cell Responses

Cytometry Part A, EarlyView.
ABSTRACT For vaccination, the mechanisms of action of antigens and of immunostimulatory pathogen‐associated molecular pattern (PAMP) adjuvants are better understood than the roles of the depot, carrier, and other formulation‐related influences. Here, we carried out cytometric studies of vaccine formulations and the effect of adjuvant formulations on B ...
Egest J. Pone, Jiin Felgner, Jenny Hernandez‐Davies, D. Huw Davies   +3 more
wiley   +1 more source

Update on Sentinel Lymph Node Methods and Pathology in Breast Cancer

Diagnostics
Breast cancer stands out as the most commonly diagnosed cancer among women globally. Precise lymph node staging holds critical significance for both predicting outcomes in early-stage disease and formulating effective treatment strategies to control ...
Jules Zhang-Yin, Etienne Mauel, Stéphanie Talpe   +2 more
doaj   +1 more source

Quantitative molecular analysis of sentinel lymph node may be predictive of axillary node status in breast cancer classified by molecular subtypes. [PDF]

PLoS ONE, 2013
To determine the performance of intraoperative one-step nucleic acid amplification (OSNA) assay in detecting sentinel lymph node metastases compared to postoperative histology taking into account breast cancer molecular classification and to evaluate ...
Simonetta Buglioni, Franco Di Filippo, Irene Terrenato, Beatrice Casini, Enzo Gallo, Ferdinando Marandino, Carlo L Maini, Rossella Pasqualoni, Claudio Botti, Simona Di Filippo, Edoardo Pescarmona, Marcella Mottolese   +11 more
doaj   +1 more source

The role of sentinel lymph nodes in breast cancer

Journal of Education, Health and Sport, 2022
Introduction. The problem of improving early diagnosis and prognosis of breast cancer remains one of the most actual for current oncological practice.
R. Nikitenko, V. Kosovan, K. Vorotyntseva, E. Koichev   +3 more
doaj   +1 more source

Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology

Barrier Immunity, EarlyView.
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley   +1 more source

Limited Sensitivity of Ultrasound‐Guided Fine‐Needle Aspiration Cytology for Occult Nodal Metastases in Early‐Stage Oral Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Ultrasound‐guided fine‐needle aspiration cytology (US‐FNAC) is commonly used in the diagnostic work‐up of head and neck cancer, but its ability to detect occult lymph node metastases in early‐stage oral squamous cell carcinoma (OSCC) with a clinically negative neck remains unclear.
Dominique N. V. Donders, Roosmarijn S. Tellman, Sammy M. Schouten, Jan Willem Dankbaar, Frank A. Pameijer, Gerben E. Breimer, Remco de Bree, Bart de Keizer   +7 more
wiley   +1 more source