Results 81 to 90 of about 1,951,350 (319)
Scientific Reports, 2022 Fibrinolytic protease (FLP) is a therapeutic enzyme used in the treatment of thrombolytic diseases. The present study proposed the concept of pH-driven swappable micellar two-phase extraction for the concurrent production and purification of FLP from ...
Ramya Muniasamy +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
NUMERICAL INVESTIGATION OF LIQUID CARRYOVER IN T-JUNCTION WITH DIFFERENT DIAMETER RATIOS
Platform, a Journal of Engineering, 2017 T-junction is commonly used in distributing two-phase flow in a piping system, especially in oil and gas industries. In offshore Malaysia, T-junction is installed at the production header as a compact separator to tap produced gas from reservoir as fuel ...
Ahmed Saieed +3 more
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
When fathers lose touch with their children after separation
, 2013 Many fathers rarely see their children after a separation, and some lose touch with them altogether. How many children are concerned? Analysing data from the French version of the Generations and Gender Survey, this chapter studies the frequency of this ...
Régnier-Loilier, Arnaud +1 more
core +1 more source
Cailiao gongchengSemiconductor photocatalytic materials exhibit significant potential for application in environmental protection，attributed to their eco-friendly and energy-efficient attributes.
YANG Yabin +6 more
doaj +1 more source
On the separation of spectra [PDF]
Proceedings of the American Mathematical Society, 1953 is of the "limit point" type for both t = oo and t = oo. Then (1) determines a boundary value problem in the Hilbert space L2( 00 oo ); that is, L(z) = (pz')' -qz is a self-adjoint operator defined on the set of functions z(t) for which z, pz' are absolutely continuous; and z, L(z) are of class L2( 00 oo).
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source