Results 131 to 140 of about 458,697 (317)

Enhanced Separation Efficiency and Purity of Circulating Tumor Cells Based on the Combined Effects of Double Sheath Fluids and Inertial Focusing. [PDF]

open access: yesFront Bioeng Biotechnol, 2021
Li BW   +12 more
europepmc   +1 more source

Temperature-Responsive Separation Membrane with High Antifouling Performance for Efficient Separation

open access: yesPolymers
Temperature-responsive separation membranes can significantly change their permeability and separation properties in response to changes in their surrounding temperature, improving efficiency and reducing membrane costs. This study focuses on the modification of polyvinylidene fluoride (PVDF) membranes with amphiphilic temperature-responsive copolymer ...
Tong Ji, Yuan Ji, Xiangli Meng, Qi Wang
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Topological defect-structured hydrogel membranes for high-efficiency permeation and selective separation

open access: yes
Biomass-derived hydrogel membranes that derived from natural polymers exhibit excellent anti-fouling properties, environmental sustainability, and molecular/ionic separation performance.
Li, Qi   +8 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Analysis of Oil Droplet Coalescence and Breakage Characteristics in Double Branch T Junction Pipe

open access: yesShiyou jixie, 2020
Existing studies do not further analyze the coalescence and breakage of oil droplets in T junction pipe, and the study on coalescence and breakage characteristics of oil droplets in double-branch T junction pipe using PBM model has not been reported.
Li Feng   +4 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Testing for Separation in Agricultural Household Models and Unobservable Individual Effects: A Note [PDF]

open access: yes
When market structure is complete, factor demands by households will be independent of their characteristics, and households will take their production decisions as if they were profit-maximizing firms.
Béatrice D'HOMBRES, Jean-Louis ARCAND
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Temperature-based tuning of magnetic particle separation by on-chip free-flow magnetophoresis

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +6 more
core  

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