Results 141 to 150 of about 458,697 (317)

Optimization on Structural Parameters of Guide Vanes Built in Cyclone Separators

Shiyou jixie
In order to study the interaction among structural parameters of the guide vanes built in cyclone separator,based on CFD numerical simulation method and BBD test design,a second-order polynomial basis function was used to build a mathematical model for ...
Zeng Yun, Chen Mi, Wei Ke, Li Meiqiu, Li Yinyin, Li Weiwei, Dong Jining   +6 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Belt separation system under slat in fattening pig housing: Effect of belt type and extraction frequency

, 2010
The efficiency of manure separation by a conveyor belt under a partially slatted floor for fattening pigs was determined for two types of belts, a flat belt with an incline of up to 6° transversely and a concave belt with an incline of up to 1 ...
Ovejero Rubio, Ismael, Mateos San Juan, Aranzazu, Alonso Peralta, Francisco, Garcimartin Molina, Miguel Angel, Vázquez Minguela, Jesús, Sanchez Espinosa, Elvira   +5 more
core   +1 more source

Numerical Simulation Study on a New Spiral Gas-Liquid Cyclone Separator

Shiyou jixie
In order to study the gas-liquid separation performance of gas-liquid cyclone separators and solve the problem of pump gas lock caused by potential high gas content in produced oil and gas fluid,a new type of spiral gas-liquid separator was designed ...
Wei Songbo, Liu Lin, Zheng Xingsheng, Wang Xinzhong, Lu Xiaohua, Ji Hao, Zhao Lixin   +6 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Construction and Investigation of a Filtration Efficiency Test System for High-Efficiency Filter Materials Based on Mass Concentration

Protection from nuclear biochemical aerosol and air pollution pays attention to aerosol mass concentration. The concentration of upstream aerosol of the commonly used filtration efficiency detection device for high-efficiency filter materials is low ...
Fang Wei, Yun Liang, Desheng Wang, Mengxiang Hu, Hao Wang, Min Tang, Lingyun Wang   +6 more
core   +1 more source

Separation analysis of macrolide antibiotics with good performance on a positively charged C18HCE column

, 2016
The separation of basic macrolide antibiotics suffers from peak tailing and poor efficiency on traditional silica-based reversed-phase liquid chromatography columns.
Wei, Jie, Yan, Jingyu, Liang, Xinmiao, Guo, Zhimou, Shen, Aijin, Zhang, Feifang, Jin, Gaowa, Yang, Bingcheng   +7 more
core   +1 more source

Development and Performance Evaluation of a Modified Separator for Enhanced Natural Gas Decontamination

Engineering Proceedings
Natural gas streams extracted from production wells often contain undesirable components such as water vapor, gas condensate, and solid particulates. These impurities reduce fuel quality and damage downstream equipment through corrosion, fouling, and ...
Akhror Uzokov, Rakhmatulla Muradov, Abdulaziz Bakhtiyorov, Tolib Turayev, Adham Norkobilov   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Optimization of the Mechanical Isolation Process of Mucilage from Chia Seeds (Salvia hispanica L.): Physicochemical, Morphological, and Rheological Characterization

Polysaccharides
This study aimed to evaluate how hydration temperature, rotational speed, and screw restriction influence the extraction efficiency, physicochemical characteristics, and monosaccharide composition of chia seed mucilage (CSM).
Frida R. Cornejo-García, Ricardo M. González-Reza, Isela Rojas-Molina, Adriana Rojas-Molina, José L. Sánchez-Millán, Carlos T. Quirino-Barreda, Elsa Gutiérrez-Cortez   +6 more
doaj   +1 more source