Results 141 to 150 of about 1,159,653 (280)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Optimization Of A Second-Order Statistics Blind Separation Algorithm For Gaussian Signals

, 2015
Arie Yeredor
openalex   +2 more sources

Statistics of bedload transport over steep slopes: Separation of time scales and collective motion [PDF]

, 2012
J. Heyman, F. Mettra, H. B. Ma, C. Ancey
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

High statistics measurement of the underground muon pair separation at Gran Sasso [PDF]

, 1999
M. Ambrosio, R. Antolini, C. Aramo, G. Auriemma, A. Baldini, G. C. Barbarino, B. C. Barish, G. Battistoni, R. Bellotti, C. Bemporad, E. Bernardini, P. Bernardini, H. Bilokon, V. Bisi, C. Bloise, C. Bower, S. Bussino, F. Cafagna, M. Calicchio, D. Campana, M. Carboni, M. Castellano, S. Cecchini, F. Cei, V. Chiarella, B. C. Choudhary, S. Coutu, G. de Cataldo, H. Dekhissi, C. De Marzo, I. De Mitri, J. E. Derkaoui, M. De Vincenzi, A. Di Credico, O. Erriquez, C. Favuzzi, C. Forti, P. Fusco, P. Giacomelli, G. Giannini, N. Giglietto, M. Giorgini, M. Grassi, L. Gray, A. Grillo, F. Guarino, C. Gustavino, A. Habig, K. Hanson, R. Heinz, Yuping Huang, E. Iarocci, E. Katsavounidis, I. Katsavounidis, E. Kearns, H. Kim, S. Kyriazopoulou, E. Lamanna, C. Lane, T. Lari, D.S. Levin, P. Lipari, N.P. Longley, M. J. Longo, F. Loparco, F. Maaroufi, G. Mancarella, G. Mandrioli, S. Manzoor, A. Margiotta Neri, A. Marini, D. Martello, A. Marzari‐Chiesa, M. N. Mazziotta, C. Mazzotta, D. G. Michael, S. Mikheyev, L. S. Miller, P. Monacelli, T. Montaruli, M. Monteno, S. Mufson, J. Musser, D. Nicolò, C. J. Orth, G. Osteria, M. Ouchrif, O. Palamara, V. Patera, L. Patrizii, R. Pazzi, C.W. Peck, S. Petrera, P. Pistilli, V. Popa, A. Rainó, Armando Rastelli, J. Reynoldson, F. Ronga, U. Rubizzo   +99 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Global research hotspots, development trends and prospect discoveries of phase separation in cancer: a decade-long informatics investigation

Biomarker Research
Liquid-liquid phase separation (LLPS) is a complex and subtle phenomenon whose formation and regulation take essential roles in cancer initiation, growth, progression, invasion, and metastasis.
Song-Bin Guo, Xue-Zhao Feng, Wei-Juan Huang, Zhen-Zhong Zhou, Xiao-Peng Tian   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Deformed Statistics Free Energy Model for Source Separation using Unsupervised Learning [PDF]

, 2011
R. C. Venkatesan, A. Plastino
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source