Results 151 to 160 of about 1,159,653 (280)
Tongxin xuebaoAiming at the problem of optimal detection of mixed signal symbol sequences, on the basis of co-frequency mixed receiving baseband signal model, sufficient statistics for joint maximum likelihood blind detection were derived, and the optimal receiver ...
YU Hongyi +4 more
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Acoustic Source Separation of Convolutive Mixtures Based on Intensity Vector Statistics
, 2008 Banu Günel +2 more
openalex +2 more sources
Non-Gaussian polymers described by alpha-stable chain statistics: Model, effective interactions in binary mixtures, and application to on-surface separation [PDF]
, 2015 M. Majka, Paweł Góra
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
A question of separation: disentangling tracer bias and gravitational non-linearity with counts-in-cells statistics [PDF]
, 2017 Cora Uhlemann +11 more
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Age-dependent vitreous separation from the macula in a clinic population
Clinical Ophthalmology, 2016 Zahid Syed,1 Michael W Stewart2 1Georgetown University, Washington, DC, 2Department of Ophthalmology, Mayo School of Medicine, Jacksonville, FL, USA Background: Vitreous degeneration begins soon after birth and accelerates throughout life.
Syed Z, Stewart MW
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