We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Determination of optimal horizontal beam angulations for canal separation in mandibular molars using cone-beam computed tomography: a retrospective image-based analysis. [PDF]
Schneider B +7 more
europepmc +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Low-level features predict perceived similarity for naturalistic images. [PDF]
A-Izzeddin EJ +3 more
europepmc +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Cointegration Approach for Vibration-Based Misalignment Detection in Rotating Machinery Under Varying Load Conditions. [PDF]
Szewczyk S +4 more
europepmc +1 more source
A new blind signal separation algorithm based on second-order statistics
Dwe Daniël Schobben, Pcw Piet Sommen
openalex +1 more source
Non-Gaussian polymers described by alpha-stable chain statistics: Model, effective interactions in binary mixtures, and application to on-surface separation [PDF]
M. Majka, Paweł Góra
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ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
<i>Orangutan</i>: An R Package for Analyzing and Visualizing Phenotypic Data in the Context of Species Descriptions and Population Comparisons. [PDF]
Torres J.
europepmc +1 more source

