Results 151 to 160 of about 1,443 (177)
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Sepia Melanin for the Local Deactivation of Matrix Metalloproteinases
ACS Macro LettersMatrix metalloproteinases (MMPs) are a family of zinc-dependent enzymes that degrade the extracellular matrix and play essential functions in wound healing and tissue remodeling. However, the long-term overexpression of MMPs is associated with a chronic wound environment.
Seth D. Edwards +3 more
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Journal of Chemical Neuroanatomy, 2015
Parkinson's disease is characterised pathologically by a relatively selective death of dopaminergic neurons in the substantia nigra of the brain. The vulnerability of these neurons appears to be linked to the pigment neuromelanin. However, as yet there is limited understanding behind the mechanisms of this disease process.
Rhiannon L, Schroeder +2 more
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Parkinson's disease is characterised pathologically by a relatively selective death of dopaminergic neurons in the substantia nigra of the brain. The vulnerability of these neurons appears to be linked to the pigment neuromelanin. However, as yet there is limited understanding behind the mechanisms of this disease process.
Rhiannon L, Schroeder +2 more
openaire +3 more sources
Pigment Cell Research, 2003
The structure of melanin extracted from the ink sac of the cuttlefish Sepia officinalis was examined for different methods of isolation and purification of the pigment. Scanning electron microscopy (SEM) images of Sepia eumelanin prepared by different procedures establish that multi‐μm‐sized aggregates reported by previous workers are generated by ...
Yan, Liu, John D, Simon
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The structure of melanin extracted from the ink sac of the cuttlefish Sepia officinalis was examined for different methods of isolation and purification of the pigment. Scanning electron microscopy (SEM) images of Sepia eumelanin prepared by different procedures establish that multi‐μm‐sized aggregates reported by previous workers are generated by ...
Yan, Liu, John D, Simon
openaire +2 more sources
Photon absorption in step-wise multi-photon activation fluorescence (SMPAF) of Sepia melanin
SPIE Proceedings, 2013Previous research has shown that melanin goes through a step-wise three-photon absorption process when the fluorescence is activated with high laser intensity. We have conducted further research using even higher laser intensity for the activation, and have shown the possibility of observing power dependence other than third-order.
Zhenhua Lai +2 more
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2010
At the moment melanins are still enigmatic bio-pigments with structure and determination methods not clearly understood for the international scientific community. Among biopolymers, melanins are unique in many aspects. Some essential biopolymers (proteins, nucleic acids and carbohydrates) are chemically well characterized and can be determined using ...
Magarelli P. +2 more
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At the moment melanins are still enigmatic bio-pigments with structure and determination methods not clearly understood for the international scientific community. Among biopolymers, melanins are unique in many aspects. Some essential biopolymers (proteins, nucleic acids and carbohydrates) are chemically well characterized and can be determined using ...
Magarelli P. +2 more
openaire +1 more source
Regulating Sepia melanin agglomerates using tailored kaolinite to accelerate skin wound healing
Colloids and Surfaces B: BiointerfacesUncontrolled hemorrhage and wound healing difficulties are significant challenges in medical care. Wounds that fail to close within a limited time frame are often associated with continuous hemorrhage, hard-to-treat infections, and chronic conditions.
Zongwang Huang +6 more
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Biochemical and Biophysical Research Communications, 2003
The melanin-free ink of the cephalopod Sepia officinalis is shown to contain a heat labile proteinaceous component toxic to a variety of cell lines, including PC12 cells. Gel filtration chromatography indicated that the toxic component was concentrated in those fractions eluted at a molecular weight higher than 100 kDa and exhibiting the highest ...
G. L. RUSSO +5 more
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The melanin-free ink of the cephalopod Sepia officinalis is shown to contain a heat labile proteinaceous component toxic to a variety of cell lines, including PC12 cells. Gel filtration chromatography indicated that the toxic component was concentrated in those fractions eluted at a molecular weight higher than 100 kDa and exhibiting the highest ...
G. L. RUSSO +5 more
openaire +7 more sources
Journal of cosmetic science, 2003
Chemically unaltered melanosomes from black hair were isolated using a mild enzymatic procedure reported by Novellino et al. involving sequential treatment of a homogenized hair sample with different protease enzymes. Time-dependent fluorescence studies show, under identical conditions, that the rate of bleaching upon NH3/H2O2 treatment of hair ...
Padmaja, Prem +3 more
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Chemically unaltered melanosomes from black hair were isolated using a mild enzymatic procedure reported by Novellino et al. involving sequential treatment of a homogenized hair sample with different protease enzymes. Time-dependent fluorescence studies show, under identical conditions, that the rate of bleaching upon NH3/H2O2 treatment of hair ...
Padmaja, Prem +3 more
openaire +1 more source
ECS Meeting Abstracts
To detect neurotransmitters, electrochemical methods are favoured due to their fast measurement times, specificity and high sensitivity. However, continuous sensing is difficult, as the redox activity of many neurotransmitters, such as dopamine or serotonin, can trigger polymerization reactions.
Joaquin Isasmendi +4 more
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To detect neurotransmitters, electrochemical methods are favoured due to their fast measurement times, specificity and high sensitivity. However, continuous sensing is difficult, as the redox activity of many neurotransmitters, such as dopamine or serotonin, can trigger polymerization reactions.
Joaquin Isasmendi +4 more
openaire +2 more sources
ACS Applied Nano Materials
Photodynamic therapy (PDT) is a promising light-triggered therapy for medical conditions, including solid tumors, and it is already being used in clinical settings. PDT relies on the use of a photosensitizer that generates cytotoxic oxygen species upon photoexcitation.
Mariana Caldas +7 more
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Photodynamic therapy (PDT) is a promising light-triggered therapy for medical conditions, including solid tumors, and it is already being used in clinical settings. PDT relies on the use of a photosensitizer that generates cytotoxic oxygen species upon photoexcitation.
Mariana Caldas +7 more
openaire +2 more sources