Results 131 to 140 of about 2,210 (155)

Representative Conformational Sampling for Chiroptical Analysis of the Flexible Dopamine Agonist Rotigotine. [PDF]

open access: yesPharmaceuticals (Basel)
Li YX   +11 more
europepmc   +1 more source

Urine sepiapterin excretion as a new diagnostic marker for sepiapterin reductase deficiency

open access: yesMolecular Genetics and Metabolism, 2015
Sepiapterin reductase deficiency (SRD) causes depletion of biogenic amines in the brain, early onset motor disorder, and intellectual disability. The diagnosticmarker for this rare disease is increased sepiapterin and biopterin in CSF.
Elisabetta Pasquini   +2 more
exaly   +2 more sources

Phase I clinical evaluation of CNSA-001 (sepiapterin), a novel pharmacological treatment for phenylketonuria and tetrahydrobiopterin deficiencies, in healthy volunteers

open access: yesMolecular Genetics and Metabolism, 2019
Tetrahydrobiopterin (BH4) is the natural cofactor of aromatic amino acid hydroxylases and essential for degradation of phenylalanine and synthesis of catecholamines and serotonin.
Nicola Longo, Nenad Blau
exaly   +2 more sources

Sepiapterin reductase: Characteristics and role in diseases

Journal of Cellular and Molecular Medicine, 2020
Ligong Lu, Yao Wu, Hongzhi Du
exaly  

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