Results 81 to 90 of about 5,703,192 (247)

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Septal myectomy for obstructive hypertrophic cardiomyopathy: Comparison of outcomes of the transapical beating-heart and transaortic on-pump approachesCentral MessagePerspective

JTCVS Open
Background: Transaortic on-pump septal myectomy (SM) is the established standard for surgical septal reduction, but transapical beating-heart SM recently has emerged as a less invasive alternative.
Younus Qamar, MBBS, Rui Li, MD, PhD, Jeffrey B. Geske, MD, Jing Fang, MD, PhD, Brian D. Lahr, MS, Alexander T. Lee, BS, Steve R. Ommen, MD, Song Wan, MD, PhD, Hartzell V. Schaff, MD, Xiang Wei, MD, PhD   +9 more
doaj   +1 more source

Genome-wide study of gene variants associated with differential cardiovascular event reduction by Pravastatin therapy [PDF]

, 2012
Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood.
Westendorp, Rudi G. J., Louie Judy Z., Packard, C., Rudi G. J. Westendorp, Louie, Judy Z., Olga A. Iakoubova, Trompet, S., David J. Stott, Ian Ford, Ford Ian, Slagboom, P. Eline, Judy Z. Louie, Sacks Frank M., David J Stott, Iakoubova Olga A., Westendorp Rudi G. J., Stott, D., Trompet, Stella, Buckley, B.M., P Eline Slagboom, Dov Shiffman, Charles M Rowland, Buckley Brendan M., Sacks, Frank, Craen, A.J.M. de, Iakoubova, Olga A., Shiffman, D., Rowland, Charles M., Devlin, James J., Frank M. Sacks, Stella Trompet, Catanese, J.J., Anton J M de Craen, de Craen Anton J. M., Naveed Sattar, Joseph J Catanese, Brendan M. Buckley, Ford, Ian, Shiffman, Dov, Rowland, C.M., Rudi G J Westendorp, Charles M. Rowl, Jukema, J.W., Sacks, F.M., Sattar, N., Jukema, J. Wouter, Catanese Joseph J., Ford, I., Catanese, Joseph J., Todd G Kirchgessner, Trompet Stella, Judy Z Louie, Sattar Naveed, Packard Christopher J., Louie, J.Z., Slagboom, P.E., Shiffman Dov, James J Devlin, Kirchgessner, Todd G., de Craen, Anton J. M., Buckley, Brendan M., Kirchgessner Todd G., Joseph J. Catanese, J. Wouter Jukema, Devlin, J.J., Westendorp, R.G.J., Packard, C.J., Frank M Sacks, Stott David J., Kirchgessner, T.G., Packard, Christopher J., Devlin James J., de Craen, A.J.M., Rowland Charles M., Jukema J. Wouter, J Wouter Jukema, Eline Slagboom, Iakoubova, O.A., Sattar, Naveed, Olga A Iakoubova, Christopher J Packard, James J. Devlin, Anton J. M. De Craen, Stott, David J., Slagboom P. Eline, Christopher J. Packard, Brendan M Buckley, Stott, D.J., Todd G. Kirchgessner   +88 more
core   +2 more sources

A case of nasal bone fracture with septal fracture reduction via closed reduction of nasal bone fracture and endoscopic septoplasty

, 2023
The nasal bone is the most common site of facial fractures. Concomitant septal fracture is present in 42.0%-96.2% of cases. The correction of nasal bone and septal fracture is important cosmetically as well as functionally.
Che Hyun Park, Jae Hwan Kwon, Tai Jung Park, Geun Woo Park   +3 more
core   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Cardiac Myosin Inhibitors (CMIs) and Surgical Referral in Patients with Hypertrophic Cardiomyopathy

Journal of Cardiovascular Development and Disease
The management of obstructive hypertrophic cardiomyopathy (HCM) has been transformed by the advent of cardiac myosin inhibitors (CMIs), such as mavacamten and aficamten.
Benedetto Ferraresi, Antonio Nenna, Mohamad Jawabra, Diletta Corrado, Andrea Faggiano, Stefano Carugo, Carmelo Dominici, Giovanni Casali, Massimo Chello, Mario Lusini   +9 more
doaj   +1 more source

Terapia de ressincronização melhora a captação do MIBI-99mTc e a função cardíaca Cardiac resynchronization therapy improves the uptake of MIBI-99mTc and cardiac function

Arquivos Brasileiros de Cardiologia, 2008
Este caso mostra a melhora proporcionada pela terapia de ressincronização cardíaca (TRC) sobre a perfusão miocárdica e o desempenho do ventrículo esquerdo (VE) avaliados pela cintilografia de perfusão miocárdica com MIBI-99mTc sincronizada ao ...
Simone Cristina Soares Brandão, Maria Clementina Giorgi, Silvana D'Orio Nishioka, Martino Martinelli Filho, José Soares Jr., José Cláudio Meneghetti   +5 more
doaj   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Alcohol Septal Ablation for Hypertrophic Cardiomyopathy Guided by Intracoronary Myocardial Contrast Echocardiography to Reduce Myocardial Damage

Journal of Medical Ultrasound
Septal reduction therapy (SRT) is indicated for drug-refractory hypertrophic obstructive cardiomyopathy (HOCM). SRT includes surgical myectomy and alcohol septal ablation (ASA).
Shao-Fu Chien, Chih-Hui Chin
doaj   +1 more source