Results 71 to 80 of about 29,905 (235)

Transapical Beating-Heart Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy After Failed Septal Reduction Therapy

The Annals of Thoracic Surgery
This study sought to report an experience of transapical beating-heart septal myectomy (TA-BSM) for obstructive hypertrophic cardiomyopathy (oHCM) after failed septal reduction therapy (SRT, including transaortic septal myectomy, alcohol septal ablation, and radiofrequency ablation of the intraventricular septum) and to compare clinical outcomes with ...
Jiangtao, Li, Yue, Chen, Xiujuan, Han, Jing, Fang, Rui, Li, Song, Wan, Xiang, Wei   +6 more
openaire   +2 more sources

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

Advanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld, C. L. Dietsche, F‐L. Born, I. Onipko, L. Blaase, P. S. Dittrich   +5 more
wiley   +1 more source

Septal myectomy for obstructive hypertrophic cardiomyopathy: Comparison of outcomes of the transapical beating-heart and transaortic on-pump approachesCentral MessagePerspective

JTCVS Open
Background: Transaortic on-pump septal myectomy (SM) is the established standard for surgical septal reduction, but transapical beating-heart SM recently has emerged as a less invasive alternative.
Younus Qamar, MBBS, Rui Li, MD, PhD, Jeffrey B. Geske, MD, Jing Fang, MD, PhD, Brian D. Lahr, MS, Alexander T. Lee, BS, Steve R. Ommen, MD, Song Wan, MD, PhD, Hartzell V. Schaff, MD, Xiang Wei, MD, PhD   +9 more
doaj   +1 more source

Terapia de ressincronização melhora a captação do MIBI-99mTc e a função cardíaca Cardiac resynchronization therapy improves the uptake of MIBI-99mTc and cardiac function

Arquivos Brasileiros de Cardiologia, 2008
Este caso mostra a melhora proporcionada pela terapia de ressincronização cardíaca (TRC) sobre a perfusão miocárdica e o desempenho do ventrículo esquerdo (VE) avaliados pela cintilografia de perfusão miocárdica com MIBI-99mTc sincronizada ao ...
Simone Cristina Soares Brandão, Maria Clementina Giorgi, Silvana D'Orio Nishioka, Martino Martinelli Filho, José Soares Jr., José Cláudio Meneghetti   +5 more
doaj   +1 more source

Commentary: Septal reduction therapy: The sooner, the better? [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2022
openaire   +2 more sources

Current status of nonsurgical septal reduction therapy in hypertrophic obstructive cardiomyopathy

Interventional Cardiology, 2013
Nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy patients has been available since 1994. Medium-term case series following alcohol septal ablation (ASA) are now available. Procedural risk is low and a significant improvement in symptom burden and left ventricular outflow tract gradient is observed in most cases.
Robert M Cooper, Adeel Shahzad, Rodney H Stables   +2 more
openaire   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Implementation of seven echocardiographic parameters of myocardial asynchrony to improve the long-term response rate of cardiac resynchronization therapy (CRT)

Cardiovascular Ultrasound, 2008
Background Cardiac resynchronization Therapy (CRT) is an effective therapy for chronic heart failure with beneficial hemodynamic effects leading to a reduction of morbidity and mortality. The responder rates, however, are low.
Baumann Gert, Grohmann Andrea, Dreger Henryk, Melzer Christoph, Richter Christoph, Bondke Hansjürgen, Schattke Sebastian, Knebel Fabian, Borges Adrian C   +8 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source