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Mitochondrial abnormalities in septic cardiomyopathy
Minerva AnestesiologicaSeptic cardiomyopathy is a common complication in patients with sepsis, and is one of the indicators of poor prognosis. Its pathogenesis is complex, involving calcium ion imbalance in cardiomyocytes, nitric oxide (NO) synthesis disorder, mitochondrial abnormalities and immune inflammatory reaction, especially mitochondrial abnormalities. In this paper,
Fang, Jin, Li-Jun, Liu
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Complexities of cardiomyopathy in septic shock
Current Opinion in Infectious DiseasesPurpose of review This review highlights the complex pathophysiology of myocardial dysfunction in septic shock and emphasizes the need for early and repeated hemodynamic assessments to improve outcome. Recent findings Septic cardiomyopathy is a complex, dynamic process driven by ...
Dennis L, Stevens, Amy E, Bryant
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Dual Behavior of Exosomes in Septic Cardiomyopathy
2017Sepsis is one of the main causes of ICU hospitalization worldwide, with a high mortality rate, and is associated with a large number of comorbidities. One of the main comorbidities associated with sepsis is septic cardiomyopathy. This process occurs mainly due to mechanisms of damage in the cardiovascular system that will lead to changes in ...
Valter Vinícius Silva, Monteiro +4 more
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[Septic circulatory shock and septic cardiomyopathy].
Der Internist, 2009Septic shock is not only a circulatory shock but is also a cardiac shock, the consequence of a potentially reversible heart impairment known as septic cardiomyopathy. Disturbances of macrocirculation as well as microcirculation, an individually heterogeneous reduction of cardiac function, and an extensive impairment of demand-oriented regulation of ...
K, Werdan +7 more
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Septic cardiomyopathy - A not yet discovered cardiomyopathy?
Experimental and clinical cardiology, 2012Myocardial depression in human sepsis was only unequivocally proven in the 1980s by the group of Parrillo, who used nuclear imaging techniques to measure heart volumes and function in intensive care patients. Heart failure in sepsis is frequently masked by a seemingly normal cardiac output. However, relative to the lowered systemic vascular resistance -
Ursula, Muller-Werdan +11 more
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Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2017
Septic cardiomyopathy is a reversible myocardial dysfunction in patients with sepsis. Depression in myocardial contractility is detected in more than 40% of patients with severe sepsis or septic shock. Sepsis-induced myocardial dysfunction (SIMD) is one of the main predictors of poor outcome in patients with sepsis.
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Septic cardiomyopathy is a reversible myocardial dysfunction in patients with sepsis. Depression in myocardial contractility is detected in more than 40% of patients with severe sepsis or septic shock. Sepsis-induced myocardial dysfunction (SIMD) is one of the main predictors of poor outcome in patients with sepsis.
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Role of Cytokines in Septic Cardiomyopathy
1998The interrelations of cytokine and nitric oxide (NO) metabolism with heart function have been best documented for the heart in sepsis. The existence of human septic myocardial depression in intensive care patients was only unequivocally proved in the 1980s by the group of Parrillo, utilizing a nuclear imaging technique.
Ursula Müller-Werdan +13 more
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Septic Cardiomyopathy: From Pathophysiology to the Clinical Setting
Cells, 2022Federico Carbone +2 more
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