Results 121 to 130 of about 126,820 (261)

New-onset septic shock in the ImmunoSep trial. [PDF]

Crit Care
Zhang R.
europepmc   +1 more source

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

Animal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu, Samantha Howe, Yang Tian, Alisun N. Watson, Jason E. Farrar, Christopher E. Randolph, Jaime Andrés Ángel Isaza, Álvaro José Uribe, Yan Huang, Michael Looper, Jiangchao Zhao, Tsungcheng Tsai   +11 more
wiley   +1 more source

Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock. [PDF]

N Engl J Med
Balamuth F, Weiss SL, Long E, Thompson GC, Artis AS, Campos AB, Borland ML, Dalziel SR, Yock-Corrales A, Singh R, Williams A, Mickiewicz B, Hickey CP, Fitzgerald JC, Laskin BL, Hickey RW, Eckerle M, Alqurashi W, Alpern E, Ambroggio L, Badawy M, Baumer-Mouradian S, Berthelot S, Clukies LD, Craig S, Curtis SJ, Davis AL, Duffy S, Eisenberg MA, Emsley JG, Festekjian A, George S, Green R, Gripp KE, Jain PG, Jani S, Joubert GI, Judge P, Kam A, Kochar A, Koutroulis I, Kwok MY, Lane RD, Lithgow A, Lloyd J, Mansour K, McManemy JK, Morris C, Phillips N, Rao A, Rogers A, Sehgal A, Shayan Y, Silverman J, Tan E, Uspal NG, Vance C, Whyte E, Huang J, Freedman SB, Babl FE, Kuppermann N, PRoMPT BOLUS Investigators of the PECARN, PERC, and PREDICT Networks.   +64 more
europepmc   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Albumin in Sepsis and Septic Shock: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Shetty USA, Sharma A, Batool AE, Hussaini H, Chaudhary S, Mohammed Abdul RH, Wei CR, Hirani S.   +7 more
europepmc   +1 more source

Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics

Animal Research and One Health, EarlyView.
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley   +1 more source

Hemodynamic monitoring in sepsis and septic shock in pediatric patients: a multicenter survey. [PDF]

Crit Care Sci
Cury CBQ, Souza DC, Araujo OR, Tonial CT, Colleti Junior J, Prata-Barbosa A, Lanziotti VS.   +6 more
europepmc   +1 more source

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

Arthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel Lovell, Nicolino Ruperto   +28 more
wiley   +1 more source

Early combination of terlipressin and norepinephrine in the treatment of patients with septic shock. [PDF]

Clinics (Sao Paulo)
Ding Z, Li M, Chen Y.
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source